Klebsiella pneumoniae strain EuSCAPE_TR290

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_TR290 is a Gram-negative, rod-shaped bacterium classified as a chemoheterotroph. It is capable of forming chains, pairs, and singles and exhibits mobility due to the presence of flagella. This strain is a facultative anaerobe, allowing it to thrive in both aerobic and anaerobic environments, with an optimal growth temperature of 37°C, categorizing it as mesophilic. This strain is associated with a variety of hosts, including Homo sapiens, Gallus gallus, and various other metazoans and plants, indicating a diverse ecological niche. Its free-living biotic relationship suggests that it can exist independently in the environment, although it is primarily known for its pathogenicity in humans. Klebsiella pneumoniae strain EuSCAPE_TR290 is implicated in a multitude of health complications, including bacteremia, urinary tract infections, pneumonia, and sepsis, among others. The strain's ability to cause severe infections underscores its significance in public health, particularly in hospital settings where antibiotic resistance may complicate treatment options. The presence of a single replicon and a double membrane structure is characteristic of this bacterium, which contributes to its survival and adaptability in various environments. Understanding the ecological role and pathogenic potential of Klebsiella pneumoniae strain EuSCAPE_TR290 is crucial for developing strategies to manage infections and mitigate its impact on human health and the environment.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_TR290

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_TR290
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_TR290 genome assembly,

Gene Summary

Adenine Count

1228573 bp

Thymine Count

1225367 bp

Guanine Count

1637552 bp

Cytosine Count

1603112 bp

Genome Length

5694604 bp

Protein-coding Genes

5169 genes

Non-Coding Genes

305 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
integrating conjugative element membrane protein, pfl_4697 familySAMEA3729886_03057Not AvailablePositive3218599 - 321905716431.0
uncharacterised proteinSAMEA3729886_03058Not AvailablePositive3219541 - 322102855759.8
Isxcc1 transposaseSAMEA3729886_03059Not AvailableNegative3221506 - 322201519773.2
TransposaseSAMEA3729886_03060Not AvailableNegative3222156 - 322243710724.0
AttlNot AvailableNot AvailablePositive3222613 - 3222629Not Available
uncharacterised proteinSAMEA3729886_03061Not AvailableNegative3222896 - 322373831846.0
Gp98SAMEA3729886_03062Not AvailableNegative3223743 - 322598086170.9
PagSAMEA3729886_03063Not AvailableNegative3226293 - 322656510251.0
Head size determination protein sidSAMEA3729886_03064Not AvailableNegative3226565 - 322732628442.9
Dna primaseSAMEA3729886_03065Not AvailableNegative3227727 - 323039997153.6

Displaying genes 81 – 90 of 5474 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total