Klebsiella pneumoniae strain EuSCAPE_TR280

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_TR280 is a Gram-negative, rod-shaped bacterium that exhibits facultative anaerobic respiration and is classified as a chemoheterotroph. This strain is capable of existing in various forms, including chains, pairs, and singles, and possesses mobility due to the presence of flagella. It has a mesophilic temperature range, with an optimal growth temperature of 37°C. As a free-living organism, EuSCAPE_TR280 has a wide array of known hosts, including Homo sapiens, Gallus gallus, and various other metazoan and plant species. This strain is associated with numerous health conditions in humans, such as bacteremia, urinary tract infections, pneumonia, and more severe conditions like sepsis and meningitis. The bacterium can lead to infections in different anatomical sites, including the liver and the respiratory system, highlighting its pathogenic potential. The strain has a single replicon and is characterized by its double membrane structure. The ability of Klebsiella pneumoniae to thrive in diverse environments and its association with a range of hosts underscore its ecological flexibility and potential for cross-species transmission. This adaptability may contribute to its role as a significant pathogen in both healthcare and community settings, emphasizing the importance of ongoing surveillance and research to understand its epidemiology and impact on health.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_TR280

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_TR280
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_TR280


Gene Summary

Adenine Count

1247620 bp

Thymine Count

1249209 bp

Guanine Count

1642205 bp

Cytosine Count

1639255 bp

Genome Length

5778289 bp

Protein-coding Genes

5168 genes

Non-Coding Genes

364 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
uncharacterised proteinSAMEA3729877_00064Not AvailableNegative70630 - 707976320.91
cys regulon transcriptional activator cysbSAMEA3729877_00065Not AvailableNegative71043 - 7201735965.2
dna topoisomerase iSAMEA3729877_00066Not AvailableNegative72363 - 7496097301.9
protein ycinSAMEA3729877_00067Not AvailablePositive75367 - 756189481.22
peptidase s49 domain-containing proteinSAMEA3729877_00068Not AvailableNegative75666 - 7674840240.9
short chain dehydrogenaseSAMEA3729877_00069Not AvailablePositive76928 - 7772829521.8
cob(i)alamin adenosyltransferaseSAMEA3729877_00070Not AvailablePositive77725 - 7831521889.1
ribosomal large subunit pseudouridine synthase bSAMEA3729877_00071Not AvailableNegative78376 - 7927833849.6
lysr family transcriptional regulatorSAMEA3729877_00072Not AvailableNegative79560 - 8045633093.2
drug/metabolite transporter permeaseSAMEA3729877_00073Not AvailablePositive80568 - 8147632002.2

Displaying genes 401 – 410 of 5532 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total