Klebsiella pneumoniae strain EuSCAPE_TR088

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_TR088 is a Gram-negative, rod-shaped bacterium that demonstrates a facultative anaerobic metabolism, utilizing a chemoheterotrophic energy source. This strain is characterized by its ability to exist in various cell arrangements, including chains, pairs, and singles. It is motile, possessing flagella, and thrives optimally at 37°C, which is consistent with mesophilic organisms. This strain has been identified as a free-living organism, with a wide range of potential hosts, including Homo sapiens, various birds, mammals, and even plants. Its pathogenicity is significant, as it is associated with numerous health complications in humans, such as bacteremia, urinary tract infections, pneumonia, and sepsis. The extensive list of health effects indicates its role as a versatile pathogen capable of causing severe infections across different systems and conditions. Klebsiella pneumoniae's ability to infect various hosts suggests a strong ecological adaptability, allowing it to thrive in diverse environments. This adaptability may contribute to its persistence in human-associated habitats and its role in opportunistic infections. The presence of a single replicon and a double membrane structure is typical for Gram-negative bacteria, facilitating its survival and pathogenic mechanisms. Overall, the ecological and biological traits of Klebsiella pneumoniae strain EuSCAPE_TR088 underscore its importance as a significant pathogen in both human health and environmental microbiology.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_TR088

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_TR088
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_TR088 genome assembly,

Gene Summary

Adenine Count

1249426 bp

Thymine Count

1248891 bp

Guanine Count

1643919 bp

Cytosine Count

1656538 bp

Genome Length

5798774 bp

Protein-coding Genes

5226 genes

Non-Coding Genes

323 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
Trna-proNot AvailableNot AvailablePositive4976083 - 4976159Not Available
Trna-leuNot AvailableNot AvailablePositive4976202 - 4976288Not Available
Trna-hisNot AvailableNot AvailablePositive4976312 - 4976387Not Available
Trna-argNot AvailableNot AvailablePositive4976443 - 4976519Not Available
transport protein yifkSAMEA3729779_04667Not AvailableNegative4976622 - 497800750146.7
putative udp-n-acetyl-d-mannosaminuronic acid transferaseSAMEA3729779_04668Not AvailableNegative4978213 - 497895328159.2
eca polymeraseSAMEA3729779_04669Not AvailableNegative4978965 - 498031151336.0
4-alpha-l-fucosyltransferaseSAMEA3729779_04670Not AvailableNegative4980308 - 498138440143.0
wzxe proteinSAMEA3729779_04671Not AvailableNegative4981381 - 498263144641.6
4-keto-6-deoxy-n-acetyl-d-hexosaminyl-(lipid carrier) aminotransferaseSAMEA3729779_04672Not AvailableNegative4982633 - 498376342214.7

Displaying genes 4821 – 4830 of 5549 in total

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total