Klebsiella pneumoniae strain EuSCAPE_TR054

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_TR054 is a Gram-negative, rod-shaped bacterium that exhibits a facultative anaerobic metabolism, utilizing a chemoheterotrophic energy source. This strain is capable of existing in various cell arrangements, including chains, pairs, and singles, and possesses flagella, indicating its mobility. With an optimal growth temperature of 37°C, EuSCAPE_TR054 falls within the mesophilic temperature range. This strain is notable for its association with various hosts, including Homo sapiens, Gallus gallus, and multiple other animal species across different taxonomic groups. It is primarily characterized as free-living, but its interactions with hosts can lead to significant health effects. EuSCAPE_TR054 is linked to a range of infections, including bacteremia, urinary tract infections, pneumonia, and more severe conditions such as sepsis and meningitis. The pathogenicity of Klebsiella pneumoniae strain EuSCAPE_TR054 highlights its role as a significant opportunistic pathogen in human health, particularly in immunocompromised individuals. Its ability to colonize a diverse range of hosts suggests potential ecological implications, as it can adapt to various environments and host defenses. This adaptability may facilitate the dissemination of antibiotic resistance genes among different species, which is a growing concern in clinical microbiology. Understanding the traits of strain EuSCAPE_TR054 is crucial for addressing its impact on public health and for developing effective treatment strategies against infections it may cause.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_TR054

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_TR054
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_TR054 genome assembly,

Gene Summary

Adenine Count

1173270 bp

Thymine Count

1180973 bp

Guanine Count

1586868 bp

Cytosine Count

1570605 bp

Genome Length

5511716 bp

Protein-coding Genes

4933 genes

Non-Coding Genes

328 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
l-fucose operon activatorSAMEA3729729_00136Not AvailableNegative132689 - 13348929252.6
deoxyribose-phosphate aldolaseSAMEA3729729_00137Not AvailablePositive133888 - 13460125902.2
putative pentose kinaseSAMEA3729729_00138Not AvailablePositive134655 - 13616055030.4
deor transcriptional regulatorSAMEA3729729_00139Not AvailablePositive136207 - 13698028302.9
arac family transcriptional regulatorSAMEA3729729_00140Not AvailableNegative137117 - 13750314816.7
oxidoreductaseSAMEA3729729_00141Not AvailablePositive138432 - 1385423820.69
lactonase drp35SAMEA3729729_00142Not AvailableNegative138594 - 13953833712.1
putative dehydrogenaseSAMEA3729729_00143Not AvailableNegative139604 - 14078543209.8
oxidoreductaseSAMEA3729729_00144Not AvailableNegative140832 - 14181836317.4
transcriptional regulatorSAMEA3729729_00145Not AvailablePositive142035 - 14294333579.3

Displaying genes 431 – 440 of 5261 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total