Klebsiella pneumoniae strain EuSCAPE_TR062

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_TR062 is a gram-negative, rod-shaped bacterium classified as a facultative anaerobe and a chemoheterotroph. This strain is notable for its mobility, facilitated by the presence of flagella, and typically exhibits a cell arrangement in chains, pairs, or singles. It thrives at an optimal temperature of 37°C, indicating its mesophilic nature. As a free-living organism, EuSCAPE_TR062 has a diverse range of potential hosts, including Homo sapiens (humans), various domesticated animals such as Gallus gallus (chickens), Sus scrofa (pigs), and Canis lupus familiaris (dogs), as well as other metazoans and plants. This broad host range suggests the organism's ecological versatility and potential for transmission across different species. Clinically, this strain is associated with a variety of significant health effects in humans, including bacteremia, urinary tract infections, pneumonia, and more severe conditions such as sepsis and meningitis. The presence of Klebsiella pneumoniae in clinical settings highlights its pathogenicity and the potential for causing serious infections, particularly in vulnerable populations such as neonates. Understanding the ecological role and pathogenic potential of Klebsiella pneumoniae strain EuSCAPE_TR062 is crucial, as it underscores the importance of monitoring this organism in both health and disease contexts. Its ability to inhabit multiple environments and host species may facilitate its survival and spread, posing ongoing challenges for public health.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_TR062

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_TR062
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_TR062 genome assembly,

Gene Summary

Adenine Count

1176352 bp

Thymine Count

1184760 bp

Guanine Count

1599941 bp

Cytosine Count

1563690 bp

Genome Length

5524743 bp

Protein-coding Genes

4948 genes

Non-Coding Genes

331 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
esterase ypfhSAMEA3729745_01078Not AvailableNegative1120581 - 112127625137.9
methionine trna cytidine acetyltransferaseSAMEA3729745_01079Not AvailableNegative1121353 - 112335672952.1
ypfj protein, zinc metalloprotease superfamilySAMEA3729745_01080Not AvailableNegative1123366 - 112424131805.4
phosphoribosylaminoimidazole-succinocarboxamide synthaseSAMEA3729745_01081Not AvailableNegative1124361 - 112507426879.4
outer membrane protein nlpbSAMEA3729745_01082Not AvailableNegative1125291 - 112632537148.0
dihydrodipicolinate synthaseSAMEA3729745_01083Not AvailableNegative1126342 - 112722031163.8
glycine cleavage system transcriptional repressorSAMEA3729745_01084Not AvailablePositive1127374 - 112794020548.5
thiol peroxidaseSAMEA3729745_01085Not AvailablePositive1127944 - 112841417598.8
permease permSAMEA3729745_01086Not AvailableNegative1128475 - 112953639223.9
exported zinc metalloprotease yfgcSAMEA3729745_01087Not AvailablePositive1129759 - 113122253637.0

Displaying genes 1311 – 1320 of 5279 in total

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total