Klebsiella pneumoniae strain EuSCAPE_TR058

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_TR058 is a Gram-negative, rod-shaped bacterium that is part of the Enterobacteriaceae family. This strain is a facultative anaerobe, capable of surviving in both aerobic and anaerobic environments. It is classified as a chemoheterotroph, utilizing organic compounds for energy. The organism typically displays a variety of cell arrangements, including chains, pairs, and singles, and possesses flagella that enable mobility. EuSCAPE_TR058 is associated with a range of hosts, including Homo sapiens, Gallus gallus, and various other metazoans and vertebrates. This broad host range indicates its ecological adaptability and potential for cross-species transmission. The strain is known for its pathogenic effects in humans, causing serious health issues such as bacteremia, urinary tract infections, pneumonia, septicemia, and liver abscesses, among others. With an optimal growth temperature of 37°C and a mesophilic temperature range, EuSCAPE_TR058 is well-suited to thrive in human-associated environments. It is nonsporulating and has a single replicon along with two membranes, typical features of many Gram-negative bacteria. The ecological insight from the presence of Klebsiella pneumoniae strain EuSCAPE_TR058 is its role as a free-living pathogen that can thrive in diverse environments, including those associated with humans and other animals. Its ability to cause significant infections across species highlights the importance of monitoring and understanding this strain within clinical and environmental contexts.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_TR058

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_TR058
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_TR058 genome assembly,

Gene Summary

Adenine Count

1173591 bp

Thymine Count

1170890 bp

Guanine Count

1561970 bp

Cytosine Count

1577752 bp

Genome Length

5484203 bp

Protein-coding Genes

4944 genes

Non-Coding Genes

264 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
Putative bacteriophage dna primaseSAMEA3729737_03062Not AvailablePositive3285412 - 328638335383.4
Dna junction-specific endonuclease rapSAMEA3729737_03063Not AvailablePositive3286380 - 328699723276.2
Putative adenine-specific dna methyltransferaseSAMEA3729737_03064Not AvailablePositive3286994 - 328763824462.9
Q proteinSAMEA3729737_03065Not AvailablePositive3287628 - 328803215127.3
Hypothetical proteinSAMEA3729737_03691Not AvailableNegative3984112 - 398496633302.7
Virion morphogenesis proteinSAMEA3729737_03692Not AvailableNegative3985295 - 398574416980.7
AttlNot AvailableNot AvailablePositive3985359 - 3985370Not Available
Tail proteinSAMEA3729737_03693Not AvailableNegative3985737 - 398620417572.0
Lysb family lysis regulatory proteinSAMEA3729737_03694Not AvailableNegative3986300 - 398673116143.6
LysozymeSAMEA3729737_03695Not AvailableNegative3986728 - 398722518486.0

Displaying genes 21 – 30 of 5208 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total