Klebsiella pneumoniae strain EuSCAPE_TR056

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_TR056 is a Gram-negative, rod-shaped bacterium characterized by its ability to form chains, pairs, or exist as singles. As a facultative anaerobe, it can thrive in both aerobic and anaerobic environments, primarily utilizing a chemoheterotrophic energy source. This strain is notable for its mobility, facilitated by the presence of flagella, and it is adapted to a mesophilic temperature range, with an optimal growth temperature of 37°C. EuSCAPE_TR056 is associated with various hosts, including Homo sapiens, Gallus gallus, and multiple other metazoan and plant species. Its pathogenic potential is significant, as it is linked to a range of health effects in humans, including bacteremia, urinary tract infections, pneumonia, and more severe conditions like sepsis and meningitis. This broad host range and the variety of diseases it can cause underline its importance in both clinical and ecological contexts. The strain is nonsporulating and exhibits a biotic relationship as a free-living organism. It has a single replicon and is surrounded by two membranes, which are characteristic of Gram-negative bacteria. The presence of these traits suggests a complex ecological role, as EuSCAPE_TR056 can adapt to various environments and hosts, potentially influencing microbial community dynamics and contributing to the incidence of infections in both human and animal populations.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_TR056

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_TR056
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_TR056 genome assembly,

Gene Summary

Adenine Count

1177402 bp

Thymine Count

1169699 bp

Guanine Count

1571745 bp

Cytosine Count

1566458 bp

Genome Length

5485304 bp

Protein-coding Genes

5009 genes

Non-Coding Genes

218 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
heme exporter permease componentSAMEA3729733_00108Not AvailablePositive116078 - 11673722862.4
cytochrome c-type biogenesis protein ccmc, putative heme lyase for ccmeSAMEA3729733_00109Not AvailablePositive116787 - 11752427428.4
cytochrome c-type biogenesis protein ccmd, interacts with ccmceSAMEA3729733_00110Not AvailablePositive117521 - 1177518394.03
cytochrome c-type biogenesis protein ccme, heme chaperoneSAMEA3729733_00111Not AvailablePositive117735 - 11819316725.2
cytochrome c heme lyase subunit ccmfSAMEA3729733_00112Not AvailablePositive118190 - 12014272312.0
cytochrome c-type biogenesis protein ccmg/dsbe, thiol:disulfide oxidoreductaseSAMEA3729733_00113Not AvailablePositive120139 - 12069321021.5
cytochrome c heme lyase subunit ccmlSAMEA3729733_00114Not AvailablePositive120693 - 12115116954.8
cytochrome c heme lyase subunit ccmhSAMEA3729733_00115Not AvailablePositive121148 - 12199030536.0
uncharacterised proteinSAMEA3729733_00116Not AvailablePositive122248 - 12303328106.0
putative acyltransferaseSAMEA3729733_00117Not AvailablePositive123074 - 12355017493.0

Displaying genes 261 – 270 of 5227 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total