Klebsiella pneumoniae strain EuSCAPE_TR052

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_TR052 is a Gram-negative, rod-shaped bacterium known for its pathogenicity in humans and various hosts, including mammals and birds. This strain is classified as a facultative anaerobe, allowing it to thrive in both aerobic and anaerobic environments, with an optimal growth temperature of 37°C, placing it within the mesophilic category. It exhibits mobility, characterized by the presence of flagella, and typically forms chains, pairs, or singles in its cellular arrangement. As a chemoheterotroph, K. pneumoniae strain EuSCAPE_TR052 derives its energy from organic compounds, which is consistent with its role as a free-living organism associated with various hosts, including Homo sapiens, Gallus gallus, and several other metazoans and plants. This strain is non-sporulating and possesses a single replicon and two membranes. The pathogenic effects of this strain are significant, causing a wide range of infections in humans, such as bacteremia, urinary tract infections, pneumonia, and sepsis, among others. Its ability to infect various hosts suggests a versatility that may contribute to its persistence in diverse environments. From an ecological perspective, the presence of K. pneumoniae strain EuSCAPE_TR052 in multiple host species highlights its potential role in the transmission of antibiotic resistance genes, further complicating treatment options for infections. Understanding its habitat and pathogenicity can help inform public health strategies aimed at controlling its spread and minimizing its impact on both human health and animal populations.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_TR052

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_TR052
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_TR052 genome assembly,

Gene Summary

Adenine Count

1214079 bp

Thymine Count

1214407 bp

Guanine Count

1609124 bp

Cytosine Count

1600403 bp

Genome Length

5638013 bp

Protein-coding Genes

0 genes

Non-Coding Genes

0 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
glutathione-regulated potassium-efflux system ancillary protein kefgSAMEA3729724_02645Not AvailablePositive2774068 - 277462821325.5
glutathione-regulated potassium-efflux system protein kefbSAMEA3729724_02646Not AvailablePositive2774615 - 277642065964.1
putative cytoplasmic proteinSAMEA3729724_02647Not AvailablePositive2776432 - 27766327497.98
fkbp-type peptidyl-prolyl cis-trans isomeraseSAMEA3729724_02648Not AvailablePositive2776726 - 277731320744.9
protein slyxSAMEA3729724_02649Not AvailableNegative2777372 - 27775908356.03
fkbp-type peptidyl-prolyl cis-trans isomerase fkpaSAMEA3729724_02650Not AvailablePositive2777813 - 277864329432.0
putative regulatorSAMEA3729724_02651Not AvailablePositive2778812 - 277953426812.1
trna 5-methylaminomethyl-2-thiouridine synthase tusdSAMEA3729724_02652Not AvailablePositive2779534 - 277992013886.4
trna 5-methylaminomethyl-2-thiouridine synthase tuscSAMEA3729724_02653Not AvailablePositive2779920 - 278027913040.6
sulfur transfer complex subunit tusbSAMEA3729724_02654Not AvailablePositive2780287 - 278057410301.4

Displaying genes 2881 – 2890 of 5428 in total

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total