Klebsiella pneumoniae strain EuSCAPE_TR052

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_TR052 is a Gram-negative, rod-shaped bacterium known for its pathogenicity in humans and various hosts, including mammals and birds. This strain is classified as a facultative anaerobe, allowing it to thrive in both aerobic and anaerobic environments, with an optimal growth temperature of 37°C, placing it within the mesophilic category. It exhibits mobility, characterized by the presence of flagella, and typically forms chains, pairs, or singles in its cellular arrangement. As a chemoheterotroph, K. pneumoniae strain EuSCAPE_TR052 derives its energy from organic compounds, which is consistent with its role as a free-living organism associated with various hosts, including Homo sapiens, Gallus gallus, and several other metazoans and plants. This strain is non-sporulating and possesses a single replicon and two membranes. The pathogenic effects of this strain are significant, causing a wide range of infections in humans, such as bacteremia, urinary tract infections, pneumonia, and sepsis, among others. Its ability to infect various hosts suggests a versatility that may contribute to its persistence in diverse environments. From an ecological perspective, the presence of K. pneumoniae strain EuSCAPE_TR052 in multiple host species highlights its potential role in the transmission of antibiotic resistance genes, further complicating treatment options for infections. Understanding its habitat and pathogenicity can help inform public health strategies aimed at controlling its spread and minimizing its impact on both human health and animal populations.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_TR052

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_TR052
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_TR052 genome assembly,

Gene Summary

Adenine Count

1214079 bp

Thymine Count

1214407 bp

Guanine Count

1609124 bp

Cytosine Count

1600403 bp

Genome Length

5638013 bp

Protein-coding Genes

0 genes

Non-Coding Genes

0 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
succinylornithine transaminaseSAMEA3729724_01605Not AvailableNegative1619407 - 162062743509.0
exodeoxyribonuclease iiiSAMEA3729724_01606Not AvailablePositive1621066 - 162187230899.6
deda family inner membrane protein ydjxSAMEA3729724_01607Not AvailablePositive1622086 - 162274223739.5
alkaline phosphataseSAMEA3729724_01608Not AvailablePositive1622729 - 162343925444.5
carboxymuconolactone decarboxylase family proteinSAMEA3729724_01609Not AvailablePositive1623436 - 162399620703.1
abc transporter, periplasmic substrate-binding protein ynjbSAMEA3729724_01610Not AvailablePositive1623999 - 162517743243.5
abc transporter permeaseSAMEA3729724_01611Not AvailablePositive1625150 - 162668554841.6
abc transporter atp-binding proteinSAMEA3729724_01612Not AvailablePositive1626685 - 162731723332.3
thiosulfate sulfurtransferase ynjeSAMEA3729724_01613Not AvailablePositive1627411 - 162871847975.5
phosphatidylglycerophosphate synthaseSAMEA3729724_01614Not AvailableNegative1628770 - 162939322008.1

Displaying genes 1891 – 1900 of 5428 in total

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total