Klebsiella pneumoniae strain EuSCAPE_BE109

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_BE109 is a gram-negative, rod-shaped bacterium that is classified as a facultative anaerobe and a chemoheterotroph. This strain is known to form chains, pairs, and singles, and possesses flagella, indicating mobility. It thrives optimally at a temperature of 37°C and falls within the mesophilic range. This organism is predominantly host-associated, with a wide array of potential hosts, including Homo sapiens, Gallus gallus, and various other metazoans and plants. Its pathogenicity in humans is significant, as it is known to cause numerous health complications, including bacteremia, urinary tract infections, pneumonia, and intra-abdominal infections. Other serious conditions attributed to this strain include liver abscesses, meningitis, and sepsis, among others. Klebsiella pneumoniae EuSCAPE_BE109 is characterized by a single replicon and is nonsporulating, suggesting a stable genome without the need for sporulation as a survival mechanism. Its presence in both free-living and host-associated environments highlights its ecological versatility. The diverse range of health effects associated with Klebsiella pneumoniae underscores its role as a significant pathogen in clinical settings, particularly in immunocompromised individuals. The strain’s adaptability to various environments and hosts reflects its evolutionary success, contributing to its persistence and potential for causing outbreaks in healthcare facilities.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_BE109

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_BE109
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_BE109 genome assembly,

Gene Summary

Adenine Count

1250671 bp

Thymine Count

1252035 bp

Guanine Count

1625751 bp

Cytosine Count

1645457 bp

Genome Length

5773914 bp

Protein-coding Genes

0 genes

Non-Coding Genes

0 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
hydroxyaromatic non-oxidative decarboxylase protein bSAMEA3727705_02743Not AvailablePositive2950555 - 295114821598.4
hydroxyaromatic non-oxidative decarboxylase protein cSAMEA3727705_02744Not AvailablePositive2951148 - 295257552522.9
hydroxyaromatic non-oxidative decarboxylase protein dSAMEA3727705_02745Not AvailablePositive2952586 - 29528229226.07
hoke proteinSAMEA3727705_02746Not AvailablePositive2953161 - 29533135613.23
dna mismatch repair protein mutsSAMEA3727705_02747Not AvailableNegative2953433 - 295599495105.4
tagaturonate reductaseSAMEA3727705_02748Not AvailableNegative2956263 - 295659513181.7
hcp family type vi secretion system effectorSAMEA3727705_02749Not AvailableNegative2957056 - 295753818079.3
hemin abc transporter atpaseSAMEA3727705_02750Not AvailableNegative2957817 - 295859628245.3
hemin abc transporter, permease proteinSAMEA3727705_02751Not AvailableNegative2958589 - 295958435141.7
periplasmic hemin-binding proteinSAMEA3727705_02752Not AvailableNegative2959584 - 296040228589.8

Displaying genes 2811 – 2820 of 5510 in total

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total