Klebsiella pneumoniae strain EuSCAPE_TR026

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_TR026 is a Gram-negative, facultative anaerobic bacterium characterized by its rod shape and mobility, facilitated by the presence of flagella. This strain is classified as a chemoheterotroph, deriving energy from organic compounds, and thrives optimally at 37°C, falling within the mesophilic temperature range. The strain exhibits a unique cell arrangement, often found in chains, pairs, or singles, and possesses a single replicon and a double membrane structure. As a free-living organism, it has been identified in various hosts, including Homo sapiens, Gallus gallus, and several other metazoans and plants, indicating a broad ecological niche. Klebsiella pneumoniae strain EuSCAPE_TR026 is known for its pathogenicity in humans, being associated with a range of serious health conditions such as bacteremia, pneumonia, urinary tract infections, and sepsis, among others. The strain's ability to cause infections in diverse hosts reflects its adaptability and potential impact on both human health and veterinary medicine. The ecological insight drawn from this strain’s traits highlights its capability to thrive in various environments and hosts, raising concerns about its role in the transmission of infections across species. The diversity of its hosts suggests that Klebsiella pneumoniae strain EuSCAPE_TR026 may play a significant role in the ecosystem as both a commensal and a pathogen, underlining the importance of monitoring its prevalence and resistance patterns in clinical settings.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_TR026

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_TR026
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_TR026 genome assembly,

Gene Summary

Adenine Count

1215699 bp

Thymine Count

1219799 bp

Guanine Count

1627858 bp

Cytosine Count

1609783 bp

Genome Length

5673139 bp

Protein-coding Genes

5181 genes

Non-Coding Genes

233 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
membrane proteinSAMEA3729678_00190Not AvailablePositive196342 - 19661710323.8
albicidin resistance proteinSAMEA3729678_00191Not AvailablePositive196839 - 19788539513.5
putative transporterSAMEA3729678_00192Not AvailableNegative197886 - 19953858178.2
ribose-phosphate pyrophosphokinaseSAMEA3729678_00193Not AvailableNegative199690 - 20063734296.6
4-diphosphocytidyl-2-c-methyl-d-erythritol kinaseSAMEA3729678_00194Not AvailableNegative200821 - 20167230676.8
outer membrane lipoprotein lolbSAMEA3729678_00195Not AvailableNegative201669 - 20228023033.3
glutamyl-trna reductaseSAMEA3729678_00196Not AvailablePositive202551 - 20380746362.6
peptide chain release factor 1SAMEA3729678_00197Not AvailablePositive203850 - 20493240364.4
n5-glutamine s-adenosyl-l-methionine-dependent methyltransferaseSAMEA3729678_00198Not AvailablePositive204932 - 20578030723.6
transcriptional regulatorSAMEA3729678_00199Not AvailablePositive205780 - 20617214831.7

Displaying genes 361 – 370 of 5414 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total