Klebsiella pneumoniae strain EuSCAPE_BE108

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_BE108 is a gram-negative, rod-shaped bacterium that functions as a facultative anaerobe, thriving optimally at 37°C within a mesophilic temperature range. This strain is characterized by its mobility, facilitated by the presence of flagella, and typically occurs in various arrangements, including chains, pairs, and singles. It is a chemoheterotroph, relying on organic compounds for energy. This strain is primarily associated with Homo sapiens but has been documented in a diverse range of hosts, including Gallus gallus (chickens), Danio rerio (zebrafish), Canis lupus familiaris (dogs), and several others across the animal kingdom. Such extensive host diversity suggests a significant ecological adaptability, allowing it to thrive in various biological environments. Klebsiella pneumoniae strain EuSCAPE_BE108 is known for its pathogenicity in humans, associated with numerous health complications such as bacteremia, urinary tract infections, pneumonia, and sepsis, among others. Its ability to cause severe infections underscores the importance of understanding its biology and ecology, particularly in relation to public health. The nonsporulating nature of this strain, combined with its extensive biotic relationships and pathogenic potential, highlights the critical need for monitoring and control measures in both healthcare settings and the environment. Understanding the ecological dynamics of Klebsiella pneumoniae can aid in developing strategies to mitigate its impact on human health and animal populations.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_BE108

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_BE108
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_BE108 genome assembly,

Gene Summary

Adenine Count

1242962 bp

Thymine Count

1241895 bp

Guanine Count

1630951 bp

Cytosine Count

1627743 bp

Genome Length

5743551 bp

Protein-coding Genes

5259 genes

Non-Coding Genes

223 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
uracil-xanthine permeaseSAMEA3727704_03917Not AvailablePositive4162074 - 416345347919.7
2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (ohcu) decarboxylaseSAMEA3727704_03918Not AvailablePositive4163431 - 416393118197.7
transthyretinSAMEA3727704_03919Not AvailablePositive4163928 - 416425411423.4
antitoxinSAMEA3727704_03920Not AvailablePositive4164619 - 416490610768.0
hipa proteinSAMEA3727704_03921Not AvailablePositive4164906 - 416622849131.3
glycoside hydrolaseSAMEA3727704_03922Not AvailableNegative4166245 - 416753748241.0
fimbrial adhesinSAMEA3727704_03923Not AvailableNegative4167679 - 416868335790.9
type 1 fimbriae anchoring protein fimdSAMEA3727704_03924Not AvailableNegative4168671 - 417117290268.3
fimbrial chaperoneSAMEA3727704_03925Not AvailableNegative4171188 - 417188325251.0
putative fimbrial-like proteinSAMEA3727704_03926Not AvailableNegative4171961 - 417252419136.1

Displaying genes 3981 – 3990 of 5482 in total

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total