Klebsiella pneumoniae strain EuSCAPE_TR025

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_TR025 is a Gram-negative, rod-shaped bacterium that exhibits a facultative anaerobic metabolism, utilizing a chemoheterotrophic energy source. This strain is significant due to its association with a variety of human and animal hosts, including Homo sapiens, Gallus gallus, and Canis lupus familiaris, among others. It is free-living and can be found in diverse biotic relationships. The bacterium typically forms chains, pairs, or exists as single cells, and possesses flagella, contributing to its mobility. EuSCAPE_TR025 thrives optimally at 37°C, indicating its mesophilic nature, with a temperature range suitable for growth within typical mammalian body temperatures. Clinically, K. pneumoniae strain EuSCAPE_TR025 is notable for its pathogenicity in humans, being implicated in numerous health conditions, such as bacteremia, urinary tract infections, pneumonia, and sepsis, among others. The strain can lead to severe infections, including neonatal sepsis and liver abscesses, which poses significant public health concerns. The presence of this strain in various hosts highlights its adaptability and potential for cross-species transmission, particularly in environments where human and animal interactions are prevalent. Understanding the ecological and biological dynamics of K. pneumoniae strain EuSCAPE_TR025 can inform strategies for infection control and prevention, especially given its capacity for causing serious health complications in both humans and animals.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_TR025

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_TR025
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_TR025 genome assembly,

Gene Summary

Adenine Count

1192215 bp

Thymine Count

1193733 bp

Guanine Count

1574836 bp

Cytosine Count

1592822 bp

Genome Length

5553606 bp

Protein-coding Genes

5055 genes

Non-Coding Genes

190 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
Antitermination protein qSAMEA3729675_03115Not AvailablePositive3305738 - 330610313572.7
Hypothetical proteinSAMEA3729675_03116Not AvailableNegative3306152 - 330695230305.0
uncharacterised proteinSAMEA3729675_03117Not AvailablePositive3307135 - 330743111246.1
Trna,type:thr,anti_codon:tgt;Not AvailableNot AvailablePositive3307697 - 3307772Not Available
Putative tellurite or colicin resistance proteinSAMEA3729675_03119Not AvailablePositive3308082 - 330850715270.2
Putative holinSAMEA3729675_03120Not AvailablePositive3309154 - 330954313130.0
Putative holinSAMEA3729675_03121Not AvailablePositive3309533 - 330981110276.9
EndolysinSAMEA3729675_03122Not AvailablePositive3309811 - 331044023108.8
uncharacterised proteinSAMEA3729675_03123Not AvailableNegative3310308 - 331074216127.3
uncharacterised proteinSAMEA3729675_03124Not AvailableNegative3310954 - 331123810884.9

Displaying genes 61 – 70 of 5245 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total