Klebsiella pneumoniae strain EuSCAPE_TR159

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_TR159 is a Gram-negative, rod-shaped bacterium that exhibits a facultative anaerobic metabolism, making it capable of thriving in both aerobic and anaerobic environments. This strain is known to be chemoheterotrophic, deriving its energy from organic compounds. It typically resides in host-associated habitats, where it can be found in various forms, including chains, pairs, and singles. EuSCAPE_TR159 is motile and possesses flagella, which may contribute to its ability to colonize different hosts. It is mesophilic, with an optimal growth temperature of 37°C, which aligns with the body temperature of many warm-blooded hosts. This bacterium has a single replicon and features a double membrane structure, characteristic of Gram-negative bacteria. Klebsiella pneumoniae strain EuSCAPE_TR159 has a diverse range of hosts, including Homo sapiens, Gallus gallus, and various Metazoa, indicating its adaptability and potential for cross-species transmission. This strain is associated with numerous health effects in humans, including bacteremia, urinary tract infections, pneumonia, and neonatal sepsis, among others. Its pathogenicity is significant, leading to severe clinical outcomes, particularly in immunocompromised individuals. Ecologically, the ability of Klebsiella pneumoniae to inhabit multiple hosts and its pathogenic potential underscore its role in human health and disease dynamics. The bacterium's presence in various environments highlights the importance of monitoring and understanding its transmission pathways to mitigate infection risks in both healthcare and community settings.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_TR159

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_TR159
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_TR159 genome assembly,

Gene Summary

Adenine Count

1158987 bp

Thymine Count

1157686 bp

Guanine Count

1555611 bp

Cytosine Count

1559944 bp

Genome Length

5432228 bp

Protein-coding Genes

4944 genes

Non-Coding Genes

175 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
adenylylsulfate kinaseSAMEA3729704_02279Not AvailableNegative2409933 - 241053822505.7
sulfate adenylyltransferaseSAMEA3729704_02280Not AvailableNegative2410538 - 241196552494.4
sulfate adenylyltransferaseSAMEA3729704_02281Not AvailableNegative2411975 - 241288335262.4
siroheme synthaseSAMEA3729704_02282Not AvailableNegative2412893 - 241430851003.1
peptidase m28SAMEA3729704_02283Not AvailablePositive2414546 - 241559238140.5
phosphoadenylyl-sulfate reductaseSAMEA3729704_02284Not AvailableNegative2415665 - 241639927874.3
sulfite reductase hemoprotein beta-componentSAMEA3729704_02285Not AvailableNegative2416498 - 241821064070.8
sulfite reductase subunit alphaSAMEA3729704_02286Not AvailableNegative2418210 - 242000966039.9
queuosine biosynthesis protein quedSAMEA3729704_02287Not AvailablePositive2420326 - 242069113860.7
queuosine biosynthesis queeSAMEA3729704_02288Not AvailableNegative2420732 - 242140324971.8

Displaying genes 2331 – 2340 of 5119 in total

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total