Klebsiella pneumoniae strain EuSCAPE_TR159

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_TR159 is a Gram-negative, rod-shaped bacterium that exhibits a facultative anaerobic metabolism, making it capable of thriving in both aerobic and anaerobic environments. This strain is known to be chemoheterotrophic, deriving its energy from organic compounds. It typically resides in host-associated habitats, where it can be found in various forms, including chains, pairs, and singles. EuSCAPE_TR159 is motile and possesses flagella, which may contribute to its ability to colonize different hosts. It is mesophilic, with an optimal growth temperature of 37°C, which aligns with the body temperature of many warm-blooded hosts. This bacterium has a single replicon and features a double membrane structure, characteristic of Gram-negative bacteria. Klebsiella pneumoniae strain EuSCAPE_TR159 has a diverse range of hosts, including Homo sapiens, Gallus gallus, and various Metazoa, indicating its adaptability and potential for cross-species transmission. This strain is associated with numerous health effects in humans, including bacteremia, urinary tract infections, pneumonia, and neonatal sepsis, among others. Its pathogenicity is significant, leading to severe clinical outcomes, particularly in immunocompromised individuals. Ecologically, the ability of Klebsiella pneumoniae to inhabit multiple hosts and its pathogenic potential underscore its role in human health and disease dynamics. The bacterium's presence in various environments highlights the importance of monitoring and understanding its transmission pathways to mitigate infection risks in both healthcare and community settings.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_TR159

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_TR159
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_TR159 genome assembly,

Gene Summary

Adenine Count

1158987 bp

Thymine Count

1157686 bp

Guanine Count

1555611 bp

Cytosine Count

1559944 bp

Genome Length

5432228 bp

Protein-coding Genes

4944 genes

Non-Coding Genes

175 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
tryptophan synthase subunit beta like proteinSAMEA3729704_01384Not AvailablePositive1499104 - 149958617856.5
uncharacterised proteinSAMEA3729704_01385Not AvailablePositive1499954 - 150083533646.4
cyn operon transcriptional activatorSAMEA3729704_01386Not AvailableNegative1500845 - 150175334152.3
putative adenosine deaminaseSAMEA3729704_01387Not AvailablePositive1501886 - 150234416757.8
cyanate transport protein cynxSAMEA3729704_01388Not AvailablePositive1502341 - 150353742236.8
plp-dependent aminotransferase yfdzSAMEA3729704_01389Not AvailableNegative1504018 - 150523245123.4
sensor proteinSAMEA3729704_01390Not AvailablePositive1505615 - 150731262535.0
response regulatory protein ypdbSAMEA3729704_01391Not AvailablePositive1507324 - 150806128681.6
glucokinaseSAMEA3729704_01392Not AvailableNegative1508115 - 150908034451.7
chloride channel proteinSAMEA3729704_01393Not AvailablePositive1509344 - 151057942681.3

Displaying genes 1501 – 1510 of 5119 in total

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total