Klebsiella pneumoniae strain EuSCAPE_TR161

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_TR161 is a Gram-negative, rod-shaped bacterium that exhibits a facultative anaerobic metabolism, functioning as a chemoheterotroph. This strain is capable of existing in various cellular arrangements, including chains, pairs, and singles. It possesses flagella, enabling mobility, and thrives optimally at a temperature of 37°C, classifying it as mesophilic. This strain is primarily host-associated, with a wide range of potential hosts that include Homo sapiens, various birds (Phasianidae, Aves), domestic animals (Canis lupus familiaris, Sus scrofa, Equidae), and aquatic species (Danio rerio, Amphibia). The biotic relationship of EuSCAPE_TR161 is categorized as free-living, allowing it to inhabit diverse environments. Klebsiella pneumoniae strain EuSCAPE_TR161 is noteworthy for its pathogenicity in humans, being implicated in several serious health conditions. It is associated with bacteremia, urinary tract infections, pneumonia, and a variety of intra-abdominal infections, among other illnesses. The spectrum of infections includes both common ailments, such as cystitis and urinary tract infections, and more severe conditions like sepsis, meningitis, and liver abscesses. The presence of this strain in various hosts highlights its ecological adaptability and potential for zoonotic transmission, underlining the importance of monitoring its prevalence and resistance patterns in both clinical and agricultural settings. Such insights emphasize the need for ongoing research into its pathogenic mechanisms and the development of effective treatment strategies.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_TR161

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_TR161
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_TR161


Gene Summary

Adenine Count

1234402 bp

Thymine Count

1237475 bp

Guanine Count

1629277 bp

Cytosine Count

1617404 bp

Genome Length

5718558 bp

Protein-coding Genes

5241 genes

Non-Coding Genes

229 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
mfs transporterSAMEA3729709_00865Not AvailablePositive919995 - 92116139962.3
superoxide dismutaseSAMEA3729709_00866Not AvailableNegative921223 - 92180421148.7
regulatory proteinSAMEA3729709_00867Not AvailablePositive922274 - 92275918274.0
lipoproteinSAMEA3729709_00868Not AvailableNegative922714 - 92358631871.6
glutaredoxin-4SAMEA3729709_00869Not AvailablePositive923927 - 92427412903.5
ribonuclease tSAMEA3729709_00870Not AvailableNegative924322 - 92496923607.1
lactoylglutathione lyaseSAMEA3729709_00871Not AvailableNegative925107 - 92551414855.5
n-ethylmaleimide reductaseSAMEA3729709_00872Not AvailableNegative925593 - 92669039404.5
transcriptional regulatorSAMEA3729709_00873Not AvailableNegative926744 - 92734322021.3
oxidoreductaseSAMEA3729709_00874Not AvailablePositive927486 - 9277259478.32

Displaying genes 971 – 980 of 5470 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total