Klebsiella pneumoniae strain EuSCAPE_BE122

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_BE122 is a Gram-negative, rod-shaped bacterium that thrives in host-associated environments. It is classified as a facultative anaerobe, allowing it to utilize both aerobic and anaerobic respiration. This strain exhibits a chemoheterotrophic metabolism, deriving energy from organic compounds. Its cell arrangement typically presents in chains, pairs, or singles. The bacterium is motile, equipped with flagella, and is optimized for growth at an optimal temperature of 37°C, although it can survive within a mesophilic temperature range. EuSCAPE_BE122 possesses a single replicon and is characterized by a double membrane structure, common to Gram-negative bacteria. Klebsiella pneumoniae strain EuSCAPE_BE122 is associated with various hosts, including Homo sapiens, domestic animals such as Gallus gallus (chickens) and Sus scrofa (pigs), as well as other metazoans and vertebrates. This broad host range indicates its ecological versatility and potential for transmission across species. Clinically, this strain is significant due to its pathogenicity in humans, where it causes a range of serious infections such as bacteremia, pneumonia, urinary tract infections, and various intra-abdominal infections. The ability of EuSCAPE_BE122 to cause severe health effects underscores the importance of monitoring and controlling its spread, especially in healthcare settings where it can lead to outbreaks of antibiotic-resistant infections. Its presence in diverse hosts further emphasizes the need for understanding its ecological role and potential reservoirs in the environment.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_BE122

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_BE122
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_BE122 genome assembly,

Gene Summary

Adenine Count

1163065 bp

Thymine Count

1167421 bp

Guanine Count

1596024 bp

Cytosine Count

1533306 bp

Genome Length

5459816 bp

Protein-coding Genes

4950 genes

Non-Coding Genes

189 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
cellulose synthase, putativeSAMEA3727718_03271Not AvailablePositive3506309 - 350711228839.7
cellulose synthase catalytic subunitSAMEA3727718_03272Not AvailablePositive3507132 - 350924379556.6
cyclic di-gmp binding proteinSAMEA3727718_03273Not AvailablePositive3509240 - 351167587818.6
cellulose synthase operon protein cSAMEA3727718_03274Not AvailablePositive3511672 - 3515724145093.0
cellulose synthase operon protein dSAMEA3727718_03275Not AvailablePositive3515724 - 351620017937.4
endoglucanaseSAMEA3727718_03276Not AvailablePositive3516212 - 351721337668.1
cellulose biosynthesis protein bcsgSAMEA3727718_03277Not AvailableNegative3517321 - 351900061935.2
inner membrane proteinSAMEA3727718_03278Not AvailableNegative3518997 - 35191947597.77
cellulose biosynthesis protein bcseSAMEA3727718_03279Not AvailableNegative3519194 - 352074758697.3
protein of uncharacterised function (duf2629)SAMEA3727718_03280Not AvailablePositive3520916 - 35211047065.37

Displaying genes 3331 – 3340 of 5139 in total

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total