Klebsiella pneumoniae strain EuSCAPE_TR158

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_TR158 is a Gram-negative, rod-shaped bacterium classified as a facultative anaerobe and a chemoheterotroph. It exhibits a diverse cell arrangement, occurring in chains, pairs, and singles. This strain is motile and possesses flagella, enabling it to navigate its environment. EuSCAPE_TR158 thrives optimally at 37°C and is categorized as mesophilic, indicating its preference for moderate temperatures. The bacterium is primarily associated with various hosts, including Homo sapiens (humans), Gallus gallus (chickens), and several other animal species such as Danio rerio (zebrafish) and Canis lupus familiaris (domestic dogs). It plays a complex role in its ecological niche, acting as a free-living organism that can inhabit diverse biological environments. Klebsiella pneumoniae strain EuSCAPE_TR158 is significant due to its pathogenicity in humans, being implicated in a wide range of health effects. These include bacteremia, urinary tract infections, pneumonia, and other serious conditions such as septicemia and liver abscesses. The strain's ability to cause infections underscores its potential impact on public health, particularly in vulnerable populations. The presence of Klebsiella pneumoniae in various hosts suggests its adaptability and the potential for zoonotic transmission, highlighting the importance of monitoring this bacterium in clinical and environmental settings. Understanding its characteristics and pathogenic mechanisms can inform strategies for managing infections and mitigating its spread in both human and animal populations.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_TR158

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_TR158
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_TR158 genome assembly,

Gene Summary

Adenine Count

1251687 bp

Thymine Count

1243936 bp

Guanine Count

1623027 bp

Cytosine Count

1646772 bp

Genome Length

5765422 bp

Protein-coding Genes

5182 genes

Non-Coding Genes

314 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
oligopeptide abc transporter substrate-binding protein oppaSAMEA3729700_01841Not AvailablePositive1976718 - 197841864553.7
queuosine biosynthesis protein quecSAMEA3729700_01842Not AvailablePositive1978485 - 197918625663.8
4-hydroxybenzoyl-coa thioesteraseSAMEA3729700_01843Not AvailableNegative1979298 - 197969915118.3
competence protein comeaSAMEA3729700_01844Not AvailableNegative1979811 - 198017912467.1
peptidyl-prolyl cis-trans isomerase dSAMEA3729700_01845Not AvailableNegative1980328 - 198220267901.4
dna-binding protein hu-betaSAMEA3729700_01846Not AvailableNegative1982417 - 19826899137.98
dna-binding atp-dependent protease laSAMEA3729700_01847Not AvailableNegative1982899 - 198525387477.3
atp-dependent clp protease atp-binding subunit clpxSAMEA3729700_01848Not AvailableNegative1985437 - 198671146296.6
atp-dependent clp protease proteolytic subunitSAMEA3729700_01849Not AvailableNegative1986962 - 198758523186.0
cell division trigger factorSAMEA3729700_01850Not AvailableNegative1987895 - 198919348115.3

Displaying genes 2111 – 2120 of 5496 in total

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total