Klebsiella pneumoniae strain EuSCAPE_TR156

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_TR156 is a Gram-negative, rod-shaped bacterium characterized by its facultative anaerobic metabolism and ability to thrive at an optimal temperature of 37°C, indicating a mesophilic nature. This strain is a chemoheterotroph, utilizing organic compounds for energy. It exhibits a variety of cell arrangements, including chains, pairs, and singles, and is motile due to the presence of flagella. This bacterium is notable for its pathogenicity in humans, being associated with several serious health effects, including bacteremia, urinary tract infections, pneumonia, and various intra-abdominal infections. Its capacity to cause a wide range of conditions, such as liver abscesses, sepsis, and neonatal infections, underscores its clinical significance. Additionally, Klebsiella pneumoniae strain EuSCAPE_TR156 has been implicated in infections across a diverse array of hosts, including Homo sapiens, Gallus gallus, and various species within Metazoa and Viridiplantae. In terms of its biological relationships, this strain is classified as free-living, yet it demonstrates a capability to inhabit host-associated environments. The presence of a single genomic replicon and a double membrane structure is consistent with its classification within the Enterobacteriaceae family. The ecological insight derived from these traits suggests that Klebsiella pneumoniae strain EuSCAPE_TR156 plays a significant role in both human health and disease, highlighting its potential as a public health concern, especially in medical settings where infections can have severe consequences.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_TR156

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_TR156
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_TR156 genome assembly,

Gene Summary

Adenine Count

1251268 bp

Thymine Count

1243255 bp

Guanine Count

1624273 bp

Cytosine Count

1643987 bp

Genome Length

5762783 bp

Protein-coding Genes

5187 genes

Non-Coding Genes

316 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
glucose-1-phosphataseSAMEA3729697_03883Not AvailablePositive4104781 - 410602845506.3
uncharacterised proteinSAMEA3729697_03884Not AvailableNegative4106097 - 41063248562.88
nad(p)h:quinone oxidoreductase, type ivSAMEA3729697_03885Not AvailableNegative4106345 - 410694120910.9
putative transmembrane proteinSAMEA3729697_03886Not AvailablePositive4107713 - 410865132843.2
uncharacterised proteinSAMEA3729697_03887Not AvailableNegative4108830 - 41089795121.8
uracil permeaseSAMEA3729697_03888Not AvailableNegative4109057 - 411037945341.1
putative flavin:nadh reductaseSAMEA3729697_03889Not AvailableNegative4110401 - 411089517665.1
reductase ruteSAMEA3729697_03890Not AvailableNegative4110906 - 411149621597.6
hydrolase or acyltransferase rutdSAMEA3729697_03891Not AvailableNegative4111493 - 411229628381.3
ring-opening amidohydrolase rutc in pyrimidine catabolism pathwaySAMEA3729697_03892Not AvailableNegative4112293 - 411268513868.7

Displaying genes 3981 – 3990 of 5503 in total

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total