Klebsiella pneumoniae strain EuSCAPE_TR130

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_TR130 is a Gram-negative, rod-shaped bacterium that exhibits a facultative anaerobic metabolism, functioning as a chemoheterotroph. This strain is characterized by its ability to exist in various cellular arrangements, including chains, pairs, and singles. It possesses flagella, enabling mobility, and has a mesophilic temperature range, with an optimal growth temperature of 37°C. This strain is primarily associated with a wide range of hosts, including Homo sapiens, Gallus gallus, and other Metazoa, indicating its versatile ecological niche. Notably, Klebsiella pneumoniae is recognized for its pathogenicity in humans, being implicated in numerous health issues such as bacteremia, urinary tract infections, pneumonia, and various intra-abdominal infections. This highlights the strain's significant clinical relevance, particularly in hospital settings where it can cause severe infections like sepsis and neonatal sepsis. Moreover, Klebsiella pneumoniae strain EuSCAPE_TR130 is nonsporulating and has a biotic relationship that is classified as free-living. The bacterium contains one replicon and is surrounded by two membranes, consistent with its classification as a Gram-negative organism. The ecological insight from this data suggests that Klebsiella pneumoniae strain EuSCAPE_TR130's adaptability to various hosts and environments, alongside its pathogenic potential, underscores the importance of monitoring this bacterium in both clinical and environmental contexts to mitigate its impact on public health.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_TR130

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_TR130
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_TR130 genome assembly,

Gene Summary

Adenine Count

1280112 bp

Thymine Count

1287261 bp

Guanine Count

1725079 bp

Cytosine Count

1649866 bp

Genome Length

5942318 bp

Protein-coding Genes

5117 genes

Non-Coding Genes

238 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
AttlNot AvailableNot AvailablePositive2908299 - 2908353Not Available
IntegraseSAMEA3729660_02724Not AvailableNegative2908393 - 290947840784.4
Repressor ciSAMEA3729660_02725Not AvailableNegative2909482 - 291010223084.5
Regulatory proteinSAMEA3729660_02726Not AvailablePositive2910203 - 29104398927.07
Regulatory protein ciiSAMEA3729660_02727Not AvailablePositive2910474 - 291098318347.2
Hypothetical proteinSAMEA3729660_02728Not AvailablePositive2911155 - 291149312774.5
Hypothetical proteinSAMEA3729660_02729Not AvailablePositive2911561 - 29117948649.21
Trar/dksa family transcriptional regulatorSAMEA3729660_02730Not AvailablePositive2911794 - 29120218282.04
Dna adenine methylaseSAMEA3729660_02731Not AvailablePositive2912018 - 291290533477.8
Replication endonucleaseSAMEA3729660_02732Not AvailablePositive2912886 - 291529192061.9

Displaying genes 1 – 10 of 5355 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total