Klebsiella pneumoniae strain EuSCAPE_TR126

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_TR126 is a Gram-negative, rod-shaped bacterium characterized as a facultative anaerobe and a chemoheterotroph. This strain displays a unique cell arrangement, often found in chains, pairs, and singles, and possesses flagella, indicating motility. The optimal growth temperature for this strain is around 37°C, placing it within the mesophilic temperature range. EuSCAPE_TR126 is associated with a variety of hosts, including Homo sapiens, Gallus gallus, and several other species across Metazoa and Viridiplantae. This broad host range suggests a significant ecological adaptability and potential for transmission among different organisms. The bacterium is known for causing a variety of health issues, particularly in humans, such as pneumonia, urinary tract infections, bacteremia, and sepsis, among others. The presence of such a wide array of pathogenic effects highlights its clinical importance and the potential severity of infections it can cause. Notably, Klebsiella pneumoniae strain EuSCAPE_TR126 does not undergo sporulation and has a single replicon along with a double membrane structure typical of Gram-negative bacteria. Its biotic relationship is classified as free-living, which may contribute to its survival and persistence in various environments. The diverse health effects associated with this strain underscore its role as a significant pathogen in healthcare settings, emphasizing the need for continued monitoring and research to understand its behaviors and impacts on both human health and broader ecological interactions.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_TR126

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_TR126
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_TR126 genome assembly,

Gene Summary

Adenine Count

1215156 bp

Thymine Count

1209339 bp

Guanine Count

1610183 bp

Cytosine Count

1625349 bp

Genome Length

5660027 bp

Protein-coding Genes

5129 genes

Non-Coding Genes

323 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
sensor kinase cussSAMEA3729654_04731Not AvailablePositive4932456 - 493388953655.9
toxin-antitoxin system proteinSAMEA3729654_04732Not AvailablePositive4933992 - 49342589997.03
putative gcn5-related n-acetyltransferaseSAMEA3729654_04733Not AvailablePositive4934269 - 493480219839.8
cupin family proteinSAMEA3729654_04734Not AvailableNegative4934850 - 493597142422.0
phage polarity suppression proteinSAMEA3729654_04735Not AvailableNegative4937100 - 493766621215.0
phage late gene regulatorSAMEA3729654_04736Not AvailableNegative4937684 - 49379299188.95
phage capsid and scaffold proteinSAMEA3729654_04737Not AvailableNegative4937926 - 493866327199.4
phage dna binding proteinSAMEA3729654_04738Not AvailablePositive4939205 - 49394719679.54
phage immunity repressor proteinSAMEA3729654_04739Not AvailablePositive4939831 - 49400257124.69
uncharacterised proteinSAMEA3729654_04740Not AvailablePositive4940022 - 49402498661.42

Displaying genes 4741 – 4750 of 5452 in total

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total