Klebsiella pneumoniae strain EuSCAPE_TR125

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_TR125 is a Gram-negative, rod-shaped bacterium that exhibits a facultative anaerobic metabolism, utilizing chemoheterotrophic energy sources. This strain is known for its mobility due to the presence of flagella and typically forms chains, pairs, or exists as single cells. It thrives optimally at 37°C, falling within a mesophilic temperature range. K. pneumoniae strain EuSCAPE_TR125 is associated with a variety of hosts, including Homo sapiens, Gallus gallus, and several other animal and plant species. Its pathogenesis is significant, as it is linked to numerous health issues in humans, including bacteremia, urinary tract infections, pneumonia, and other severe conditions such as meningitis and sepsis. The strain is nonsporulating and has a single replicon with a double membrane structure. The ecological insight derived from the traits of K. pneumoniae strain EuSCAPE_TR125 suggests that its adaptability to diverse hosts, including mammals, birds, and even plants, underlines its potential for opportunistic infections. The capacity to inhabit various ecological niches may facilitate its transmission and survival in different environments, ultimately contributing to its clinical relevance and the challenges it poses in healthcare settings. Understanding its pathogenicity and biotic relationships is essential for developing strategies to manage infections caused by this strain.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_TR125

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_TR125
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_TR125 genome assembly,

Gene Summary

Adenine Count

1171542 bp

Thymine Count

1172209 bp

Guanine Count

1564576 bp

Cytosine Count

1574966 bp

Genome Length

5483293 bp

Protein-coding Genes

4983 genes

Non-Coding Genes

189 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
outer membrane protein romaSAMEA3729652_01283Not AvailablePositive1329583 - 133068341211.2
transcriptional activator ramaSAMEA3729652_01284Not AvailablePositive1330714 - 133105513496.0
putative inner membrane proteinSAMEA3729652_01285Not AvailableNegative1331073 - 13313219487.1
uncharacterised proteinSAMEA3729652_01286Not AvailableNegative1331511 - 13316213997.1
cation-transporting p-type atpaseSAMEA3729652_01287Not AvailablePositive1331824 - 133454798533.1
rnd efflux membrane fusion proteinSAMEA3729652_01288Not AvailablePositive1334600 - 133567938756.3
rnd multidrug efflux transporter, acriflavin resistance proteinSAMEA3729652_01289Not AvailablePositive1335693 - 1338785111450.0
lipoproteinSAMEA3729652_01290Not AvailableNegative1339134 - 133985326494.5
carboxylate-amine ligaseSAMEA3729652_01291Not AvailableNegative1339901 - 134101641798.6
drug/metabolite transporter permeaseSAMEA3729652_01292Not AvailableNegative1341138 - 134206132180.5

Displaying genes 1411 – 1420 of 5172 in total

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total