Klebsiella pneumoniae strain EuSCAPE_TR112

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_TR112 is a Gram-negative, rod-shaped bacterium characterized by its facultative anaerobic metabolism and chemoheterotrophic energy source. This strain can be found in various habitats associated with hosts, including Homo sapiens and several animal species such as Gallus gallus, Sus scrofa, and Danio rerio. One notable feature of this bacterium is its cellular arrangement, which can be observed as chains, pairs, or singles. EuSCAPE_TR112 possesses flagella, enabling motility, and has a mesophilic temperature range, with an optimal growth temperature of 37°C. The bacterium is nonsporulating and has a single replicon and two membranes. Klebsiella pneumoniae is recognized for its pathogenicity in humans, being implicated in a wide range of health issues. These include serious conditions such as bacteremia, urinary tract infections, pneumonia, intra-abdominal infections, and sepsis, among others. The strain's ability to cause infections in both humans and a variety of animal hosts highlights its adaptability and potential for zoonotic transmission. Understanding the ecological role of Klebsiella pneumoniae strain EuSCAPE_TR112 is crucial as it sheds light on its interactions within host-associated environments. Its pathogenic nature, coupled with the wide variety of potential hosts, indicates a significant impact on public health and underscores the importance of monitoring and managing infections caused by this bacterium in both human and veterinary contexts.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_TR112

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_TR112
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_TR112 genome assembly,

Gene Summary

Adenine Count

1362172 bp

Thymine Count

1359575 bp

Guanine Count

1671073 bp

Cytosine Count

1705379 bp

Genome Length

6098199 bp

Protein-coding Genes

5083 genes

Non-Coding Genes

305 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
uncharacterised proteinSAMEA3729818_00112Not AvailablePositive118309 - 1184013306.18
uncharacterised proteinSAMEA3729818_00113Not AvailablePositive119188 - 1193104445.7
4-aminobutyraldehyde dehydrogenaseSAMEA3729818_00114Not AvailableNegative119651 - 12107850528.8
spermidine putrescine abc transporter permease potcSAMEA3729818_00115Not AvailableNegative121101 - 12190728874.7
spermidine putrescine abc transporter permease potbSAMEA3729818_00116Not AvailableNegative121897 - 12282633647.3
putrescine transport atp-binding protein potaSAMEA3729818_00117Not AvailableNegative122828 - 12384136507.9
abc transporter, periplasmic spermidine putrescine-binding protein potdSAMEA3729818_00118Not AvailableNegative123858 - 12500342222.3
gntr family transcriptional regulatorSAMEA3729818_00119Not AvailableNegative125308 - 12672052580.4
uncharacterised proteinSAMEA3729818_00120Not AvailableNegative126841 - 1269393734.88
cytochrome bd2SAMEA3729818_00121Not AvailablePositive127408 - 12880551569.5

Displaying genes 371 – 380 of 5388 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total