Klebsiella pneumoniae strain EuSCAPE_TR106

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_TR106 is a Gram-negative, rod-shaped bacterium that exhibits a facultative anaerobic metabolism, utilizing chemoheterotrophic energy sources. This strain is notable for its mobility, facilitated by the presence of flagella, and it typically exists in chains, pairs, or as single cells. Optimal growth occurs at 37°C, falling within a mesophilic temperature range. The strain is associated with various hosts, including Homo sapiens, Gallus gallus, and multiple other Metazoa and Viridiplantae species. This broad host range underscores its ecological versatility and potential impact on both human and animal health. K. pneumoniae is known for its pathogenicity in humans, being implicated in a range of serious health conditions, such as bacteremia, urinary tract infections, pneumonia, meningitis, and sepsis. Its role in these infections is significant, particularly in hospital settings where it can cause outbreaks of healthcare-associated infections. The strain does not undergo sporulation, which may influence its survivability and transmission dynamics in various environments. With a single replicon and a double membrane structure, EuSCAPE_TR106 exemplifies characteristics typical of many Enterobacteriaceae. The ecological insight from this data suggests that K. pneumoniae strain EuSCAPE_TR106’s capacity to thrive in diverse habitats and its association with both human and animal hosts may facilitate its dissemination and persistence in the environment, thereby contributing to its role as a prominent opportunistic pathogen.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_TR106

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_TR106
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_TR106 genome assembly,

Gene Summary

Adenine Count

1170321 bp

Thymine Count

1173289 bp

Guanine Count

1573461 bp

Cytosine Count

1572367 bp

Genome Length

5489438 bp

Protein-coding Genes

4966 genes

Non-Coding Genes

283 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
fusaric acid resistance protein fusb, fuscSAMEA3729807_03469Not AvailablePositive3663896 - 366586373225.6
ribonuclease inhibitorSAMEA3729807_03470Not AvailablePositive3665943 - 366621810748.5
ycfr family proteinSAMEA3729807_03471Not AvailableNegative3666269 - 36665359332.13
protein ycfrSAMEA3729807_03472Not AvailableNegative3666634 - 36668979296.06
arginine pathway regulatory protein argrSAMEA3729807_03473Not AvailableNegative3667273 - 366774317039.6
malate dehydrogenaseSAMEA3729807_03474Not AvailablePositive3668158 - 366909632428.3
outer membrane stress sensor protease degsSAMEA3729807_03475Not AvailableNegative3669233 - 367029137125.8
serine endoproteaseSAMEA3729807_03476Not AvailableNegative3670379 - 367174647273.3
cytochrome d ubiquinol oxidase subunit iiiSAMEA3729807_03477Not AvailableNegative3671920 - 367231815046.8
atpaseSAMEA3729807_03478Not AvailablePositive3672509 - 367363642498.3

Displaying genes 3481 – 3490 of 5249 in total

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total