Klebsiella pneumoniae strain EuSCAPE_TR100

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_TR100 is a Gram-negative, rod-shaped bacterium that exhibits a facultative anaerobic metabolism, primarily relying on chemoheterotrophy for energy. This strain is known for its mobility, facilitated by the presence of flagella, and demonstrates diverse cellular arrangements, including chains, pairs, and singles. EuSCAPE_TR100 thrives optimally at 37°C within a mesophilic temperature range. This bacterium is associated with various hosts, including Homo sapiens, Gallus gallus, and several other metazoan species, indicating its ecological versatility. It is notably free-living, yet it has significant pathogenic potential in humans, contributing to a wide range of serious health issues. These include bacteremia, pneumonia, urinary tract infections, and various intra-abdominal infections, among others. Its pathogenicity is underscored by its ability to cause conditions such as neonatal sepsis and emphysematous pyelonephritis. Klebsiella pneumoniae strain EuSCAPE_TR100 is nonsporulating and possesses two membranes, characteristic of its Gram-negative classification. The strain's genetic information is cataloged under the accession UJQV00000000.1, signifying its identification in microbial databases. In summary, Klebsiella pneumoniae strain EuSCAPE_TR100 exemplifies the complexity of microbial life, particularly its ability to adapt to different hosts while posing significant health risks to humans. Its role in various infections highlights the importance of understanding such pathogens within both clinical and ecological contexts, emphasizing the need for vigilant monitoring and control measures in healthcare settings.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_TR100

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_TR100
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_TR100 genome assembly,

Gene Summary

Adenine Count

1182345 bp

Thymine Count

1186221 bp

Guanine Count

1584085 bp

Cytosine Count

1586008 bp

Genome Length

5538659 bp

Protein-coding Genes

4994 genes

Non-Coding Genes

288 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
putative fimbrial subunitSAMEA3729799_02915Not AvailablePositive3090392 - 309094018866.0
fimbrial proteinSAMEA3729799_02916Not AvailablePositive3090960 - 309205737997.5
acetate permease actpSAMEA3729799_02917Not AvailableNegative3092104 - 309375959128.8
membrane proteinSAMEA3729799_02918Not AvailableNegative3093756 - 309406711371.2
acetyl-coa synthetaseSAMEA3729799_02919Not AvailableNegative3094251 - 309620971942.6
glutamate-aspartate carrier proteinSAMEA3729799_02920Not AvailablePositive3096622 - 309793547125.1
sel1 repeat proteinSAMEA3729799_02921Not AvailableNegative3097972 - 309865824837.0
formate dehydrogenase-hSAMEA3729799_02922Not AvailableNegative3098888 - 310056762526.8
formate dehydrogenase-hSAMEA3729799_02923Not AvailableNegative3100616 - 310103515199.4
response regulator proteinSAMEA3729799_02924Not AvailablePositive3101308 - 310203626369.0

Displaying genes 3071 – 3080 of 5282 in total

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total