Klebsiella pneumoniae strain EuSCAPE_RS118

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_RS118 is a gram-negative, rod-shaped bacterium that exhibits a facultative anaerobic metabolism, functioning as a chemoheterotroph. This strain is capable of mobility due to the presence of flagella and typically exists in various cell arrangements, including chains, pairs, and singles. It thrives optimally at 37°C and falls within the mesophilic temperature range. The strain is primarily host-associated, with a biotic relationship described as free-living. It has a wide host range, including Homo sapiens, Gallus gallus, and various other metazoan species, indicating its versatility and adaptability in different ecological niches. Klebsiella pneumoniae is recognized for its pathogenic potential in humans, being implicated in a range of serious health effects. These include bacteremia, urinary tract infections, pneumonia, and intra-abdominal infections, among others. The strain is associated with severe conditions such as sepsis and neonatal sepsis, highlighting its relevance in clinical settings. With a single replicon and a dual membrane structure, Klebsiella pneumoniae strain EuSCAPE_RS118 exemplifies the complex biology of pathogenic bacteria. Its ability to thrive in diverse environments and its association with significant health issues underscore the importance of monitoring and understanding its ecological dynamics, particularly in relation to human health and disease transmission.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_RS118

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_RS118
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_RS118 genome assembly,

Gene Summary

Adenine Count

1227431 bp

Thymine Count

1230737 bp

Guanine Count

1638296 bp

Cytosine Count

1606512 bp

Genome Length

5702976 bp

Protein-coding Genes

5096 genes

Non-Coding Genes

308 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
triphosphoribosyl-dephospho-coa transferaseSAMEA3727545_04060Not AvailablePositive4321583 - 432242529176.2
malonate decarboxylase delta subunitSAMEA3727545_04061Not AvailablePositive4322443 - 432274210537.5
malonate decarboxylase subunit betaSAMEA3727545_04062Not AvailablePositive4322735 - 432356829675.4
malonate decarboxylase subunit gammaSAMEA3727545_04063Not AvailablePositive4323568 - 432436828255.9
auxin efflux carrierSAMEA3727545_04064Not AvailablePositive4324505 - 432546433318.4
phosphoribosyl-dephospho-coa transferaseSAMEA3727545_04065Not AvailablePositive4325468 - 432608523015.5
malonyl coa-acyl carrier protein transacylaseSAMEA3727545_04066Not AvailablePositive4326085 - 432698732167.0
malonate utilization transcriptional regulatorSAMEA3727545_04067Not AvailableNegative4326977 - 432790334652.4
uncharacterised proteinSAMEA3727545_04068Not AvailablePositive4328553 - 432973444596.4
malate:quinone oxidoreductaseSAMEA3727545_04069Not AvailableNegative4330293 - 433193960006.4

Displaying genes 4131 – 4140 of 5404 in total

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total