Klebsiella pneumoniae strain EuSCAPE_RS118

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_RS118 is a gram-negative, rod-shaped bacterium that exhibits a facultative anaerobic metabolism, functioning as a chemoheterotroph. This strain is capable of mobility due to the presence of flagella and typically exists in various cell arrangements, including chains, pairs, and singles. It thrives optimally at 37°C and falls within the mesophilic temperature range. The strain is primarily host-associated, with a biotic relationship described as free-living. It has a wide host range, including Homo sapiens, Gallus gallus, and various other metazoan species, indicating its versatility and adaptability in different ecological niches. Klebsiella pneumoniae is recognized for its pathogenic potential in humans, being implicated in a range of serious health effects. These include bacteremia, urinary tract infections, pneumonia, and intra-abdominal infections, among others. The strain is associated with severe conditions such as sepsis and neonatal sepsis, highlighting its relevance in clinical settings. With a single replicon and a dual membrane structure, Klebsiella pneumoniae strain EuSCAPE_RS118 exemplifies the complex biology of pathogenic bacteria. Its ability to thrive in diverse environments and its association with significant health issues underscore the importance of monitoring and understanding its ecological dynamics, particularly in relation to human health and disease transmission.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_RS118

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_RS118
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_RS118 genome assembly,

Gene Summary

Adenine Count

1227431 bp

Thymine Count

1230737 bp

Guanine Count

1638296 bp

Cytosine Count

1606512 bp

Genome Length

5702976 bp

Protein-coding Genes

5096 genes

Non-Coding Genes

308 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
inner membrane proteinSAMEA3727545_02830Not AvailablePositive3014784 - 301519416082.8
flavodoxin 2SAMEA3727545_02831Not AvailableNegative3015201 - 301572219515.1
tyrosine recombinase xerdSAMEA3727545_02832Not AvailablePositive3015823 - 301671933969.1
thiol:disulfide interchange protein dsbcSAMEA3727545_02833Not AvailablePositive3016742 - 301745525457.8
ssdna-specific exonuclease recjSAMEA3727545_02834Not AvailablePositive3017461 - 301919462996.1
peptide chain release factor 2SAMEA3727545_02835Not AvailablePositive3019416 - 302037835905.0
lysyl-trna synthetaseSAMEA3727545_02836Not AvailablePositive3020388 - 302190557549.6
isopentenyl-diphosphate delta-isomeraseSAMEA3727545_02837Not AvailableNegative3022140 - 302269420672.5
inner membrane protein yqgaSAMEA3727545_02838Not AvailableNegative3022748 - 302346424839.0
3-polyprenyl-4-hydroxybenzoate carboxy-lyase ubixSAMEA3727545_02839Not AvailableNegative3023477 - 302405520950.7

Displaying genes 3011 – 3020 of 5404 in total

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total