Klebsiella pneumoniae strain EuSCAPE_RS115

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_RS115 is a Gram-negative, rod-shaped bacterium that exhibits a variety of significant traits. It is a facultative anaerobe, allowing it to thrive in both aerobic and anaerobic environments. This strain is classified as a chemoheterotroph, utilizing organic compounds for energy. Its cellular arrangement can be observed in chains, pairs, or as singles, and it possesses flagella, indicating its mobility. EuSCAPE_RS115 is mesophilic, with an optimal growth temperature of 37°C, which corresponds with the human body temperature, suggesting a close association with human hosts. This strain is free-living but is known to inhabit a range of hosts, including Homo sapiens, Gallus gallus, and various other vertebrates and invertebrates. The pathogenicity of Klebsiella pneumoniae strain EuSCAPE_RS115 primarily affects humans, being associated with numerous health issues such as bacteremia, urinary tract infections, pneumonia, and sepsis. The extensive list of potential infections underscores its clinical significance and highlights the need for continued monitoring and research. With a single replicon and a double membrane structure, this bacterium reflects typical characteristics of the Enterobacteriaceae family. The diverse range of hosts and the spectrum of infections caused by this strain emphasize its ecological adaptability and potential impact on both human and animal health. Understanding its ecological role and pathogenic mechanisms is vital for developing effective strategies to manage infections caused by this organism.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_RS115

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_RS115
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_RS115 genome assembly,

Gene Summary

Adenine Count

1211186 bp

Thymine Count

1206757 bp

Guanine Count

1599762 bp

Cytosine Count

1583633 bp

Genome Length

5601338 bp

Protein-coding Genes

5017 genes

Non-Coding Genes

349 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
Hypothetical proteinSAMEA3727542_00327Not AvailablePositive309778 - 31044624464.9
Hypothetical proteinSAMEA3727542_00328Not AvailablePositive310446 - 31079312507.5
Hypothetical proteinSAMEA3727542_00329Not AvailablePositive310796 - 31122115537.8
Hypothetical proteinSAMEA3727542_00330Not AvailablePositive311218 - 31160114075.1
Major tail proteinSAMEA3727542_00331Not AvailablePositive311664 - 31240725840.0
Hypothetical proteinSAMEA3727542_00332Not AvailablePositive312465 - 31314225083.3
Hypothetical proteinSAMEA3727542_00333Not AvailableNegative313370 - 31384317353.8
Regulatory proteinSAMEA3727542_00334Not AvailableNegative313846 - 3140798767.6
Hypothetical proteinSAMEA3727542_00335Not AvailablePositive314181 - 3143275684.91
Putative antirepressor proteinSAMEA3727542_00336Not AvailablePositive314395 - 31511427484.4

Displaying genes 51 – 60 of 5366 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total