Klebsiella pneumoniae strain EuSCAPE_RS109

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_RS109 is a Gram-negative, facultative anaerobic bacterium characterized by its rod shape and presence of flagella, allowing for mobility. It typically exists in various arrangements, including chains, pairs, and singles. This strain is classified as a chemoheterotroph, deriving its energy from organic compounds, and is mesophilic, with an optimal growth temperature of 37°C. EuSCAPE_RS109 is associated with a wide range of hosts, including Homo sapiens, Gallus gallus, and various other metazoans, plants, and vertebrates like Danio rerio and Canis lupus familiaris. Its health effects on humans are significant, as it is known to cause various serious infections, including bacteremia, urinary tract infections, pneumonia, and sepsis. This strain is particularly notable for its involvement in neonatal sepsis and pyogenic liver abscesses, highlighting its pathogenic potential. The strain does not form spores, which is a key trait for its survival strategy. Instead, it thrives in host-associated environments, indicating its adaptation to living in proximity to a variety of hosts. Given its ability to cause a wide range of infections, EuSCAPE_RS109 underscores the need for ongoing monitoring in both clinical and environmental settings. Understanding its interactions within host organisms and its potential for pathogenicity can provide insights into the epidemiology of Klebsiella pneumoniae and the challenges it poses to public health.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_RS109

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_RS109
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_RS109 genome assembly,

Gene Summary

Adenine Count

1141597 bp

Thymine Count

1146429 bp

Guanine Count

1536232 bp

Cytosine Count

1539330 bp

Genome Length

5363588 bp

Protein-coding Genes

4919 genes

Non-Coding Genes

130 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
AttlNot AvailableNot AvailablePositive416014 - 416034Not Available
Putative tail protein (tape measure)SAMEA3727536_00369Not AvailableNegative421129 - 424194107549.0
uncharacterised proteinSAMEA3727536_00370Not AvailableNegative424202 - 42452812004.3
uncharacterised proteinSAMEA3727536_00371Not AvailableNegative424528 - 4246986315.88
uncharacterised proteinSAMEA3727536_00372Not AvailableNegative424882 - 42535517555.1
Putative single-stranded dna-binding proteinSAMEA3727536_00373Not AvailableNegative425724 - 42608912824.9
Dna primaseSAMEA3727536_00374Not AvailableNegative426576 - 42927297409.6
uncharacterised proteinSAMEA3727536_00375Not AvailableNegative429265 - 42961512481.8
Hypothetical proteinSAMEA3727536_00376Not AvailableNegative429625 - 43025122742.5
uncharacterised proteinSAMEA3727536_00377Not AvailableNegative430248 - 4304577893.55

Displaying genes 1 – 10 of 5049 in total

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Pyogenic liver abscessCausesPMC12392612
Pyogenic liver abscessesCausesPMC12392612
Liver abscessesCausesPMC12392612
Urinary tract infectionsCausesPMC12915344
PneumoniaCausesPMC12915344
BacteremiaCausesPMC12915344
Liver abscessesCausesPMC12915344
EndophthalmitisCausesPMC12915344
MeningitisCausesPMC12915344
Bloodstream infectionsCausesPMC13168211

Displaying health effects 11 – 20 of 53 in total