Klebsiella pneumoniae strain EuSCAPE_RS109

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_RS109 is a Gram-negative, facultative anaerobic bacterium characterized by its rod shape and presence of flagella, allowing for mobility. It typically exists in various arrangements, including chains, pairs, and singles. This strain is classified as a chemoheterotroph, deriving its energy from organic compounds, and is mesophilic, with an optimal growth temperature of 37°C. EuSCAPE_RS109 is associated with a wide range of hosts, including Homo sapiens, Gallus gallus, and various other metazoans, plants, and vertebrates like Danio rerio and Canis lupus familiaris. Its health effects on humans are significant, as it is known to cause various serious infections, including bacteremia, urinary tract infections, pneumonia, and sepsis. This strain is particularly notable for its involvement in neonatal sepsis and pyogenic liver abscesses, highlighting its pathogenic potential. The strain does not form spores, which is a key trait for its survival strategy. Instead, it thrives in host-associated environments, indicating its adaptation to living in proximity to a variety of hosts. Given its ability to cause a wide range of infections, EuSCAPE_RS109 underscores the need for ongoing monitoring in both clinical and environmental settings. Understanding its interactions within host organisms and its potential for pathogenicity can provide insights into the epidemiology of Klebsiella pneumoniae and the challenges it poses to public health.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_RS109

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_RS109
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_RS109 genome assembly,

Gene Summary

Adenine Count

1141597 bp

Thymine Count

1146429 bp

Guanine Count

1536232 bp

Cytosine Count

1539330 bp

Genome Length

5363588 bp

Protein-coding Genes

4919 genes

Non-Coding Genes

130 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
twin arginine translocase protein eSAMEA3727536_02273Not AvailableNegative2456766 - 24569727257.89
amidaseSAMEA3727536_02274Not AvailableNegative2457215 - 245800328376.4
protein crcbSAMEA3727536_02275Not AvailablePositive2458093 - 245847613665.0
cold shock protein cspeSAMEA3727536_02276Not AvailableNegative2458544 - 24587537449.81
antimicrobial peptide resistance and lipid a acylation pagpSAMEA3727536_02277Not AvailableNegative2458948 - 245946619768.9
c4-dicarboxylate transporter dcucSAMEA3727536_02278Not AvailablePositive2459805 - 246117847980.9
ribonuclease iSAMEA3727536_02279Not AvailablePositive2461271 - 246206829137.7
regulator of nucleoside diphosphate kinaseSAMEA3727536_02280Not AvailablePositive2462247 - 246265714868.8
universal stress protein gSAMEA3727536_02281Not AvailablePositive2462844 - 246327215953.4
alkyl hydroperoxide reductase protein fSAMEA3727536_02282Not AvailableNegative2463349 - 246491456036.0

Displaying genes 2281 – 2290 of 5049 in total

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total