Klebsiella pneumoniae strain EuSCAPE_BE098

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_BE098 is a Gram-negative, rod-shaped bacterium that exhibits a facultative anaerobic metabolism, deriving energy as a chemoheterotroph. This strain is notable for its capability to exist in various arrangements, including chains, pairs, and singles, and it possesses flagella, indicating motility. Optimal growth occurs at 37°C, with a mesophilic temperature range, and it has a singular replicon and a double membrane structure. This strain is primarily associated with hosts such as Homo sapiens, Gallus gallus, and various other vertebrates, showcasing its versatility in different biological environments. K. pneumoniae is recognized for its pathogenic potential, causing a wide range of serious health issues in humans, including bacteremia, urinary tract infections, pneumonia, and sepsis. The bacterium is implicated in various infections, such as intra-abdominal infections and liver abscesses, highlighting its significant role in clinical settings. Ecologically, K. pneumoniae's ability to inhabit diverse hosts and its free-living biotic relationship suggest a broad ecological adaptability. Its presence across multiple species indicates potential zoonotic transmission and raises concerns regarding its impact on both human and animal health. The strain's pathogenicity underscores the importance of understanding its behavior in various environments, particularly given the rising incidence of antibiotic-resistant strains in clinical scenarios. This emphasizes the need for ongoing surveillance and research to mitigate the health risks associated with K. pneumoniae infections.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_BE098

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_BE098
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_BE098 genome assembly,

Gene Summary

Adenine Count

1205268 bp

Thymine Count

1209893 bp

Guanine Count

1616618 bp

Cytosine Count

1601609 bp

Genome Length

5633388 bp

Protein-coding Genes

5030 genes

Non-Coding Genes

417 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
pts system phosphoenolpyruvate-protein phosphotransferaseSAMEA3727685_00839Not AvailablePositive883941 - 88566863271.3
pts system proteinSAMEA3727685_00840Not AvailablePositive885711 - 88622018248.1
uncharacterised proteinSAMEA3727685_00841Not AvailableNegative886261 - 8865008761.6
pyridoxal kinaseSAMEA3727685_00842Not AvailableNegative886497 - 88736331193.4
transcriptional regulator of pyridoxine metabolismSAMEA3727685_00843Not AvailablePositive887446 - 88874446380.6
yybh proteinSAMEA3727685_00844Not AvailablePositive888885 - 88928014687.6
cysteine synthase bSAMEA3727685_00845Not AvailableNegative889277 - 89018832644.1
sulfate and thiosulfate import atp-binding protein cysaSAMEA3727685_00846Not AvailableNegative890307 - 89140140844.3
sulfate transport system permease protein cyswSAMEA3727685_00847Not AvailableNegative891391 - 89226632288.3
sulfate transport system permease protein cystSAMEA3727685_00848Not AvailableNegative892266 - 89309930312.7

Displaying genes 1201 – 1210 of 5447 in total

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total