Klebsiella pneumoniae strain EuSCAPE_BE085

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_BE085 is a Gram-negative, rod-shaped bacterium that exhibits a facultative anaerobic lifestyle, allowing it to thrive in both aerobic and anaerobic environments. This strain is classified as a chemoheterotroph, relying on organic compounds as its energy source. It can be found in various arrangements, including chains, pairs, and singles, and possesses flagella, indicating mobility. EuSCAPE_BE085 is mesophilic, with an optimal growth temperature of 37°C, making it well-suited for colonization in warm-blooded hosts. Its diverse host range includes Homo sapiens, various mammals (e.g., Canis lupus familiaris, Sus scrofa, and Equidae), birds (e.g., Phasianidae and Gallus gallus), amphibians, and even plants (Viridiplantae). This strain is known for its significant pathogenic potential in humans, being associated with a wide array of health complications such as bacteremia, urinary tract infections, pneumonia, and sepsis, among others. The ability to cause such infections underscores its role as a significant opportunistic pathogen, particularly in immunocompromised individuals. Ecologically, the presence of K. pneumoniae strain EuSCAPE_BE085 in various environments and hosts highlights its adaptability and potential for interspecies transmission. This adaptability may facilitate the spread of antibiotic resistance genes, posing challenges in clinical settings and necessitating ongoing surveillance and research to understand its impact on public health.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_BE085

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_BE085
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_BE085 genome assembly,

Gene Summary

Adenine Count

1223129 bp

Thymine Count

1224332 bp

Guanine Count

1622143 bp

Cytosine Count

1630150 bp

Genome Length

5699754 bp

Protein-coding Genes

5021 genes

Non-Coding Genes

452 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
ribulokinaseSAMEA3727672_02255Not AvailableNegative2378870 - 238057961662.0
arabinose operon regulatory proteinSAMEA3727672_02256Not AvailablePositive2380917 - 238176232194.3
deda family inner membrane protein yabiSAMEA3727672_02257Not AvailablePositive2381891 - 238265828409.0
thiamin abc transporter, atpase component thiqSAMEA3727672_02258Not AvailableNegative2382645 - 238334625156.7
thiamin abc transporter transmembrane proteinSAMEA3727672_02259Not AvailableNegative2383330 - 238494058920.9
thiamin abc transporterSAMEA3727672_02260Not AvailableNegative2384916 - 238589936093.2
sgrrSAMEA3727672_02261Not AvailableNegative2386189 - 238784464140.7
uncharacterised proteinSAMEA3727672_02262Not AvailablePositive2387932 - 23880845788.87
transport proteinSAMEA3727672_02263Not AvailablePositive2388352 - 238953642561.5
transporter anion:cation symporter (acs) familySAMEA3727672_02264Not AvailableNegative2389570 - 239088048152.6

Displaying genes 2561 – 2570 of 5473 in total

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total