Klebsiella pneumoniae strain EuSCAPE_BE091

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_BE091 is a Gram-negative, rod-shaped bacterium that is classified as a facultative anaerobe and a chemoheterotroph, indicating its ability to thrive in varying oxygen levels while obtaining energy from organic compounds. This strain exhibits mobility, facilitated by the presence of flagella, and typically forms arrangements of chains, pairs, or singles. The preferred habitat for EuSCAPE_BE091 is host-associated environments, with a broad range of potential hosts including Homo sapiens, Gallus gallus, and various other metazoans, as well as some plant species. This diversity underscores its adaptability across different biological kingdoms. Klebsiella pneumoniae is notorious for its pathogenicity in humans, being associated with a wide array of severe health effects. These include bacteremia, urinary tract infections, pneumonia, and more serious conditions like sepsis and meningitis. The strain's ability to cause such infections emphasizes its significance in clinical settings, particularly in immunocompromised or hospitalized patients. With a mesophilic temperature range, this bacterium thrives optimally at around 37°C, aligning with the human body temperature, which may facilitate its role as a pathogen. The presence of a single replicon and a double membrane structure are characteristic of its cellular organization, while its nonsporulating nature suggests a reliance on existing host environments for survival. The ecological insight provided by the traits of Klebsiella pneumoniae strain EuSCAPE_BE091 indicates its capacity to occupy diverse niches and its prominent role in human health as both a commensal and a pathogen, highlighting the complexities of microbial interactions within host-associated ecosystems.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_BE091

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_BE091
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_BE091 genome assembly,

Gene Summary

Adenine Count

1194774 bp

Thymine Count

1201413 bp

Guanine Count

1602038 bp

Cytosine Count

1587617 bp

Genome Length

5585842 bp

Protein-coding Genes

4984 genes

Non-Coding Genes

420 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
l-arabinose transporter permease proteinSAMEA3727678_03110Not AvailablePositive3210886 - 321186634069.8
trehalose-6-phosphate phosphataseSAMEA3727678_03111Not AvailablePositive3212028 - 321281628537.9
alpha,alpha-trehalose-phosphate synthaseSAMEA3727678_03112Not AvailablePositive3212791 - 321421553802.1
universal stress protein cSAMEA3727678_03113Not AvailableNegative3214239 - 321466715728.1
rhamnogalacturonide transporter rhitSAMEA3727678_03114Not AvailablePositive3215021 - 321660458212.8
rhamnogalacturonides degradation protein rhinSAMEA3727678_03115Not AvailablePositive3216609 - 321774843818.5
arginyl-trna synthetaseSAMEA3727678_03116Not AvailableNegative3217810 - 321954364246.1
protein yecmSAMEA3727678_03117Not AvailablePositive3219779 - 322034821097.1
cytoplasmic copper homeostasis protein cutcSAMEA3727678_03118Not AvailablePositive3220425 - 322116826485.1
trna (5-methoxyuridine) 34 synthaseSAMEA3727678_03119Not AvailableNegative3221250 - 322225438228.9

Displaying genes 3251 – 3260 of 5404 in total

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total