Klebsiella pneumoniae strain EuSCAPE_BE088

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_BE088 is a Gram-negative, rod-shaped bacterium characterized as a facultative anaerobe. It is a chemoheterotroph that typically resides in host-associated environments, demonstrating versatility in its energy acquisition. This strain can be found in various arrangements, including chains, pairs, and singles, and is motile due to the presence of flagella. Optimal growth occurs at 37°C, placing this strain within the mesophilic temperature range. It possesses a single replicon and features a double membrane structure, which is characteristic of Gram-negative bacteria. Klebsiella pneumoniae strain EuSCAPE_BE088 is notably pathogenic to humans, causing a range of serious health issues, including bacteremia, urinary tract infections, pneumonia, and various intra-abdominal infections. The strain has also been associated with more severe conditions such as sepsis and meningitis, highlighting its clinical significance. This bacterium is free-living but has a diverse host range that includes Homo sapiens, various avian species, and other metazoans such as Gallus gallus (chickens) and Danio rerio (zebrafish). The presence of this strain in multiple hosts suggests its ecological adaptability and potential for zoonotic transmission, raising concerns about its role in public health. Understanding its pathogenicity and host interactions is critical for developing effective treatment and prevention strategies against infections caused by Klebsiella pneumoniae.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_BE088

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_BE088
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_BE088


Gene Summary

Adenine Count

1254818 bp

Thymine Count

1256889 bp

Guanine Count

1639485 bp

Cytosine Count

1680642 bp

Genome Length

5831834 bp

Protein-coding Genes

5193 genes

Non-Coding Genes

359 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
cfa/i fimbrial subunit c usher proteinSAMEA3727675_01649Not AvailableNegative1752706 - 175523190738.1
cfa/i fimbrial auxiliary subunitSAMEA3727675_01650Not AvailableNegative1755257 - 175592524309.2
fimbrillin matbSAMEA3727675_01651Not AvailableNegative1755984 - 175657120077.5
regulator of cfa/i fimbriaeSAMEA3727675_01652Not AvailableNegative1756646 - 175718821179.7
phosphonate transport atp-binding proteinSAMEA3727675_01653Not AvailablePositive1758036 - 175887830657.2
phosphonate abc transporter substrate-binding proteinSAMEA3727675_01654Not AvailablePositive1758901 - 175983933604.3
putative inner membrane permease of abc transporterSAMEA3727675_01655Not AvailablePositive1759906 - 176077832284.1
phosphonate abc transporter permeaseSAMEA3727675_01656Not AvailablePositive1760775 - 176165932888.9
putative receptorSAMEA3727675_01657Not AvailablePositive1761755 - 176258828250.7
phosphoserine phosphataseSAMEA3727675_01658Not AvailableNegative1762962 - 176362724308.2

Displaying genes 1931 – 1940 of 5552 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total