Klebsiella pneumoniae strain EuSCAPE_BE088

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_BE088 is a Gram-negative, rod-shaped bacterium characterized as a facultative anaerobe. It is a chemoheterotroph that typically resides in host-associated environments, demonstrating versatility in its energy acquisition. This strain can be found in various arrangements, including chains, pairs, and singles, and is motile due to the presence of flagella. Optimal growth occurs at 37°C, placing this strain within the mesophilic temperature range. It possesses a single replicon and features a double membrane structure, which is characteristic of Gram-negative bacteria. Klebsiella pneumoniae strain EuSCAPE_BE088 is notably pathogenic to humans, causing a range of serious health issues, including bacteremia, urinary tract infections, pneumonia, and various intra-abdominal infections. The strain has also been associated with more severe conditions such as sepsis and meningitis, highlighting its clinical significance. This bacterium is free-living but has a diverse host range that includes Homo sapiens, various avian species, and other metazoans such as Gallus gallus (chickens) and Danio rerio (zebrafish). The presence of this strain in multiple hosts suggests its ecological adaptability and potential for zoonotic transmission, raising concerns about its role in public health. Understanding its pathogenicity and host interactions is critical for developing effective treatment and prevention strategies against infections caused by Klebsiella pneumoniae.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_BE088

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_BE088
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_BE088


Gene Summary

Adenine Count

1254818 bp

Thymine Count

1256889 bp

Guanine Count

1639485 bp

Cytosine Count

1680642 bp

Genome Length

5831834 bp

Protein-coding Genes

5193 genes

Non-Coding Genes

359 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
thiosulfate sulfurtransferase glpeSAMEA3727675_01308Not AvailablePositive1416120 - 141644912269.3
intramembrane serine protease glpgSAMEA3727675_01309Not AvailablePositive1416506 - 141733030865.6
glycerol-3-phosphate regulon repressorSAMEA3727675_01310Not AvailablePositive1417380 - 141813827912.5
transcriptional regulator maltSAMEA3727675_01311Not AvailableNegative1418154 - 1420859103117.0
maltodextrin phosphorylaseSAMEA3727675_01312Not AvailablePositive1421484 - 142387490078.4
4-alpha-glucanotransferaseSAMEA3727675_01313Not AvailablePositive1423885 - 142597878544.7
high-affinity gluconate transporter gnttSAMEA3727675_01314Not AvailableNegative1426081 - 142739746138.8
nfua fe-s protein maturationSAMEA3727675_01315Not AvailableNegative1427733 - 142830821005.8
protein gntxSAMEA3727675_01316Not AvailableNegative1428367 - 142904125393.3
pimeloyl-bioc--coa transferase biohSAMEA3727675_01317Not AvailablePositive1429080 - 142985328265.4

Displaying genes 1651 – 1660 of 5552 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total