Klebsiella pneumoniae strain EuSCAPE_BE082

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_BE082 is a Gram-negative, rod-shaped bacterium that exists as a facultative anaerobe. It can be found in various arrangements, including chains, pairs, and singles. This strain is motile and possesses flagella, which enhances its mobility. It is a chemoheterotroph, deriving energy from organic compounds. EuSCAPE_BE082 is mesophilic, with an optimal growth temperature of 37°C, making it well-suited to thrive in the human body and other warm-blooded hosts. It has a unique habitat association, primarily linked to Homo sapiens, but it can also be found in a variety of other hosts, including Gallus gallus (chickens), various Metazoa, Viridiplantae (plants), Danio rerio (zebrafish), Ovis aries (sheep), Phasianidae (pheasants), Sus scrofa (pigs), Aves (birds), Canis lupus familiaris (domestic dogs), Amphibia (amphibians), and Equidae (horses). Pathogenically, Klebsiella pneumoniae EuSCAPE_BE082 is significant, associated with a wide range of serious health effects, including bacteremia, urinary tract infections, pneumonia, and various types of abscesses. The strain is known to cause severe conditions such as sepsis, neonatal sepsis, and emphysematous pyelonephritis, highlighting its potential impact on both human and animal health. This strain’s ability to infect multiple hosts suggests a versatile ecological role, indicating its adaptation to various environments and hosts, thereby contributing to its persistence in different ecosystems and its relevance in clinical microbiology.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_BE082

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_BE082
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_BE082 genome assembly,

Gene Summary

Adenine Count

1216652 bp

Thymine Count

1207913 bp

Guanine Count

1593500 bp

Cytosine Count

1604158 bp

Genome Length

5622223 bp

Protein-coding Genes

5019 genes

Non-Coding Genes

391 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
Replication endonucleaseSAMEA3727669_00064Not AvailableNegative54427 - 5684192364.4
Dna adenine methyltransferaseSAMEA3727669_00065Not AvailableNegative56838 - 5769532166.0
Zinc-finger containing proteinSAMEA3727669_00066Not AvailableNegative57692 - 579198309.21
Hypothetical proteinSAMEA3727669_00067Not AvailableNegative57919 - 581528678.29
Hypothetical proteinSAMEA3727669_00068Not AvailableNegative58220 - 5856112853.7
Cell division blocking proteinSAMEA3727669_00069Not AvailableNegative58525 - 587257716.53
Regulatory proteinSAMEA3727669_00070Not AvailableNegative58733 - 5924218224.1
Rha family transcriptional regulatorSAMEA3727669_00071Not AvailableNegative59275 - 595179242.27
P2 ci-like proteinSAMEA3727669_00072Not AvailablePositive59634 - 6026623015.4
Site-specific integraseSAMEA3727669_00073Not AvailablePositive60270 - 6131039168.6

Displaying genes 61 – 70 of 5410 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total