Klebsiella pneumoniae strain EuSCAPE_BE079

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_BE079 is a Gram-negative, rod-shaped bacterium that demonstrates a facultative anaerobic metabolism, utilizing a chemoheterotrophic energy source. This strain exhibits mobility, attributed to the presence of flagella, and typically appears in various arrangements, including chains, pairs, and singles. It has a mesophilic temperature range, with an optimal growth temperature of 37°C, aligning with the typical human body temperature. This strain has significant pathogenic potential, being associated with a variety of serious health effects in humans, including bacteremia, pneumonia, urinary tract infections, and liver abscesses, among others. Klebsiella pneumoniae is known for its role as a pathogen in both nosocomial and community-acquired infections, affecting not only humans (Homo sapiens) but also a diverse range of hosts such as domestic animals (e.g., Gallus gallus and Sus scrofa) and other vertebrates. K. pneumoniae strain EuSCAPE_BE079 is nonsporulating and possesses a single replicon and a double membrane structure, characteristic of Gram-negative bacteria. Its ability to live freely in various environments and its association with multiple host species illustrate its ecological versatility and potential for transmission across different ecological niches. The presence of this strain in both clinical and environmental contexts emphasizes the need for ongoing surveillance and research to understand its pathogenic mechanisms and the implications for public health. Understanding its interactions within diverse habitats can provide insights into the dynamics of bacterial transmission and infection control strategies.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_BE079

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_BE079
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_BE079 genome assembly,

Gene Summary

Adenine Count

1272968 bp

Thymine Count

1267079 bp

Guanine Count

1658396 bp

Cytosine Count

1655838 bp

Genome Length

5854281 bp

Protein-coding Genes

5072 genes

Non-Coding Genes

422 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
Tail fiberSAMEA3727666_02816Not AvailablePositive2938084 - 294054689035.9
Hypothetical proteinSAMEA3727666_02817Not AvailablePositive2940601 - 29408769842.53
Hypothetical proteinSAMEA3727666_02818Not AvailablePositive2940989 - 294139314098.2
Putative holinSAMEA3727666_02819Not AvailablePositive2941380 - 294168511354.1
EndolysinSAMEA3727666_02820Not AvailablePositive2941675 - 294230423148.8
Tail proteinSAMEA3727666_02821Not AvailablePositive2942500 - 29427759627.58
Putative portal proteinSAMEA3727666_02927Not AvailableNegative3052456 - 305371547249.1
AttlNot AvailableNot AvailablePositive3053404 - 3053417Not Available
Terminase large subunitSAMEA3727666_02928Not AvailableNegative3053888 - 305560964722.4
Putative small terminase subunitSAMEA3727666_02929Not AvailableNegative3055609 - 305604315585.8

Displaying genes 181 – 190 of 5494 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total