Klebsiella pneumoniae strain EuSCAPE_BE071

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_BE071 is a Gram-negative, rod-shaped bacterium that exhibits a facultative anaerobic metabolism. It is classified as a chemoheterotroph, utilizing organic compounds for energy. This strain typically exists in host-associated habitats, demonstrating a free-living biotic relationship. It is capable of mobility, possessing flagella, and exhibits a diverse cell arrangement characterized by chains, pairs, and singles. EuSCAPE_BE071 thrives optimally at 37°C, within a mesophilic temperature range, and has a single replicon with a double-membrane structure. The strain has been identified in a wide array of hosts, including Homo sapiens (humans), various birds, mammals, and reptiles such as Danio rerio (zebrafish) and Sus scrofa (domestic pigs). This strain is notable for its pathogenicity in humans, being associated with a range of serious health effects. These include bacteremia, urinary tract infections, pneumonia, and a variety of intra-abdominal infections. Additionally, it can lead to conditions such as sepsis, neonatal sepsis, and pyogenic liver abscesses. The broad range of infections and host species indicates a significant ecological versatility and adaptability of Klebsiella pneumoniae strain EuSCAPE_BE071, highlighting its potential impact on both human health and animal hosts. This adaptability may contribute to its persistence and spread in various environments, emphasizing the importance of monitoring this strain in clinical and ecological contexts.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_BE071

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_BE071
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_BE071 genome assembly,

Gene Summary

Adenine Count

1222253 bp

Thymine Count

1223359 bp

Guanine Count

1637208 bp

Cytosine Count

1621011 bp

Genome Length

5703831 bp

Protein-coding Genes

5094 genes

Non-Coding Genes

421 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
conjugal transfer protein travSAMEA3727659_05366Not AvailableNegative5562346 - 556291520519.4
conjugal transfer protein trapSAMEA3727659_05367Not AvailableNegative5562938 - 556353422006.2
conjugal transfer pilus assembly protein trabSAMEA3727659_05368Not AvailableNegative5563527 - 556443231914.8
transposaseSAMEA3727659_05369Not AvailableNegative5564863 - 556549823937.9
transcriptional regulatorSAMEA3727659_05370Not AvailableNegative5565606 - 556647531330.0
phosphonate dehydrogenase (nad-dependent phosphite dehydrogenase)SAMEA3727659_05371Not AvailableNegative5566469 - 556747936399.1
phosphate abc transporter permeaseSAMEA3727659_05372Not AvailableNegative5567488 - 556831529460.7
abc-type phosphate/phosphonate transport system, periplasmic componentSAMEA3727659_05373Not AvailableNegative5568324 - 556918731321.6
atp-binding protein of phosphonate abc transporterSAMEA3727659_05374Not AvailableNegative5569184 - 557001129711.0
transposaseSAMEA3727659_05375Not AvailablePositive5570353 - 557067312404.2

Displaying genes 5391 – 5400 of 5515 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total