Klebsiella pneumoniae strain EuSCAPE_BE062

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_BE062 is a Gram-negative, rod-shaped bacterium that demonstrates facultative anaerobic growth and exhibits mobility due to the presence of flagella. This strain is classified as a chemoheterotroph, deriving energy from organic compounds. It thrives optimally at a temperature of 37°C, within a mesophilic temperature range, and can be found in various cell arrangements including chains, pairs, and singles. K. pneumoniae EuSCAPE_BE062 is associated with a wide array of hosts including Homo sapiens and various animal species such as Gallus gallus, Sus scrofa, and Canis lupus familiaris, among others. This broad host range indicates its ecological versatility and potential for zoonotic transmission. The bacterium is known for its pathogenicity in humans, being implicated in numerous health conditions, such as bacteremia, urinary tract infections, pneumonia, and various forms of sepsis. This strain is nonsporulating and has a complex cellular structure with two membranes. The presence of a single replicon suggests a relatively straightforward genomic organization, which may influence its adaptability and virulence. The ecological insight derived from K. pneumoniae EuSCAPE_BE062's traits highlights its role as a free-living organism that can thrive in diverse environments while posing significant health risks to both humans and animals. Its ability to infect multiple hosts underscores the importance of monitoring this pathogen in public health contexts and veterinary medicine.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_BE062

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_BE062
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_BE062 genome assembly,

Gene Summary

Adenine Count

1262650 bp

Thymine Count

1269534 bp

Guanine Count

1670350 bp

Cytosine Count

1634835 bp

Genome Length

5837369 bp

Protein-coding Genes

5278 genes

Non-Coding Genes

208 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
aldehyde dehydrogenaseSAMEA3727651_00351Not AvailablePositive364380 - 36586453090.0
putative periplasmic proteinSAMEA3727651_00352Not AvailablePositive366260 - 36734239060.8
putative tonb-dependent receptorSAMEA3727651_00353Not AvailablePositive367402 - 36960079242.6
phenylalanine transporterSAMEA3727651_00354Not AvailablePositive369708 - 37108450004.6
nucleoside permease nupgSAMEA3727651_00355Not AvailablePositive371236 - 37247745347.6
inosose isomeraseSAMEA3727651_00356Not AvailablePositive372494 - 37351638070.9
oxidoreductaseSAMEA3727651_00357Not AvailablePositive373518 - 37466942252.5
lipoproteinSAMEA3727651_00358Not AvailableNegative374689 - 37510514949.4
luxr family transcriptional regulatorSAMEA3727651_00359Not AvailablePositive375837 - 37647224511.3
cfa/i fimbrial chaperoneSAMEA3727651_00360Not AvailableNegative376479 - 37716225814.9

Displaying genes 491 – 500 of 5486 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total