Klebsiella pneumoniae strain EuSCAPE_BE059

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_BE059 is a Gram-negative, rod-shaped bacterium that primarily exists in host-associated environments, demonstrating a facultative anaerobic metabolism as a chemoheterotroph. This strain is capable of mobility due to the presence of flagella and typically arranges itself in chains, pairs, or as singles. Its optimal growth temperature is 37°C, and it thrives within a mesophilic temperature range. This strain has significant clinical relevance, being associated with a variety of health effects in humans, including bacteremia, urinary tract infections, pneumonia, and sepsis, among others. It is known to cause serious conditions such as pyogenic liver abscesses, meningitis, and enteritis, highlighting its pathogenicity in human hosts. Notably, Klebsiella pneumoniae can also infect a range of other hosts including birds, fish, and mammals, suggesting its adaptability to various biological environments. With only one replicon and two membranes, Klebsiella pneumoniae strain EuSCAPE_BE059 is nonsporulating and engages in a free-living biotic relationship. The broad host range indicates its ecological versatility, allowing it to exploit different niches for survival and reproduction. Understanding the host associations and pathogenic potential of this strain is crucial, particularly in the context of antibiotic resistance and public health. The ability to cause infections in diverse species underscores the importance of monitoring its spread and the need for effective control measures in clinical and environmental settings.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_BE059

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_BE059
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_BE059 genome assembly,

Gene Summary

Adenine Count

1293864 bp

Thymine Count

1291431 bp

Guanine Count

1691825 bp

Cytosine Count

1688653 bp

Genome Length

5965773 bp

Protein-coding Genes

5435 genes

Non-Coding Genes

342 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
Tail proteinSAMEA3727648_00313Not AvailablePositive329156 - 32960816611.8
Tail proteinSAMEA3727648_00314Not AvailablePositive329969 - 33023810152.0
P2 gpogr-like protein (acttivation of late gene expression)SAMEA3727648_00315Not AvailablePositive330306 - 3305218093.62
uncharacterised proteinSAMEA3727648_00316Not AvailablePositive330679 - 3309008268.73
trka, potassium channel-family proteinSAMEA3727648_00317Not AvailableNegative331122 - 33280760418.1
AttrNot AvailableNot AvailablePositive332949 - 332960Not Available
inner membrane proteinSAMEA3727648_00318Not AvailablePositive333074 - 33345714113.8
GlutaredoxinSAMEA3727648_00319Not AvailableNegative333464 - 3337279839.71
Transposase insfSAMEA3727648_01218Not AvailableNegative1330374 - 13305838209.7
Transposase insfSAMEA3727648_01219Not AvailableNegative1330593 - 13308479768.14

Displaying genes 11 – 20 of 5777 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total