Klebsiella pneumoniae strain EuSCAPE_BE049

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_BE049 is a gram-negative, rod-shaped bacterium that exhibits a facultative anaerobic metabolism, functioning as a chemoheterotroph. This strain is known for its mobility, facilitated by the presence of flagella, and typically forms arrangements in chains, pairs, or singles. It thrives optimally at 37°C, placing it within the mesophilic temperature range. EuSCAPE_BE049 is primarily associated with various hosts, including Homo sapiens (humans), domesticated animals such as Gallus gallus (chickens) and Sus scrofa (pigs), as well as several other vertebrates and invertebrates. The strain is notable for its significant health impacts on humans, being linked to a range of serious infections including bacteremia, pneumonia, urinary tract infections, sepsis, and liver abscesses, among others. This bacterium has a biotic relationship characterized as free-living, with a single replicon and two membranes. The variety of hosts and the pathogenicity of K. pneumoniae strain EuSCAPE_BE049 highlight its ecological versatility and potential as a significant opportunistic pathogen in both human and animal health contexts. Given its capacity to cause multiple types of infections, understanding its transmission dynamics and environmental reservoirs may inform better strategies for managing its impact on public health.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_BE049

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_BE049
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_BE049 genome assembly,

Gene Summary

Adenine Count

1202949 bp

Thymine Count

1204855 bp

Guanine Count

1602084 bp

Cytosine Count

1605938 bp

Genome Length

5615826 bp

Protein-coding Genes

5014 genes

Non-Coding Genes

338 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
Putative tail fiber proteinSAMEA3727639_01946Not AvailableNegative2046480 - 204752334004.3
Hypothetical proteinSAMEA3727639_01947Not AvailableNegative2047525 - 204811221722.8
Hypothetical proteinSAMEA3727639_01948Not AvailableNegative2048105 - 204933742934.3
Hypothetical proteinSAMEA3727639_01949Not AvailableNegative2049345 - 204970112750.3
AttlNot AvailableNot AvailablePositive2049565 - 2049578Not Available
uncharacterised proteinSAMEA3727639_01950Not AvailableNegative2049778 - 205056629647.3
Putative baseplate proteinSAMEA3727639_01951Not AvailableNegative2050566 - 205115320797.6
Hypothetical proteinSAMEA3727639_01952Not AvailableNegative2051143 - 205201231118.5
Putative structural proteinSAMEA3727639_01953Not AvailableNegative2052009 - 205231411387.6
Hypothetical proteinSAMEA3727639_01954Not AvailableNegative2052316 - 205315529847.8

Displaying genes 1 – 10 of 5352 in total

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Pyogenic liver abscessCausesPMC12392612
Pyogenic liver abscessesCausesPMC12392612
Liver abscessesCausesPMC12392612
Urinary tract infectionsCausesPMC12915344
PneumoniaCausesPMC12915344
BacteremiaCausesPMC12915344
Liver abscessesCausesPMC12915344
EndophthalmitisCausesPMC12915344
MeningitisCausesPMC12915344
Bloodstream infectionsCausesPMC13168211

Displaying health effects 11 – 20 of 53 in total