Klebsiella pneumoniae strain EuSCAPE_BE036

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_BE036 is a Gram-negative, rod-shaped bacterium that displays a facultative anaerobic metabolism, functioning as a chemoheterotroph. This strain exhibits diverse cell arrangements, including chains, pairs, and singles, and possesses flagella, which contribute to its mobility. It thrives optimally at 37°C, indicating its mesophilic nature. This bacterium is primarily associated with a variety of hosts, including Homo sapiens (humans), Gallus gallus (chickens), and several other metazoan and plant species. Its pathogenicity is notably significant in humans, where it is linked to a wide range of health issues, including bacteremia, urinary tract infections, pneumonia, and several intra-abdominal infections. The strain is implicated in serious conditions such as sepsis, neonatal sepsis, and various abscesses, highlighting its potential for causing severe disease. Klebsiella pneumoniae strain EuSCAPE_BE036 is characterized by its free-living biotic relationship, indicating its ability to survive independently in various environments. Despite its pathogenic potential, its ecological role in different biological systems, including interactions with both animals and plants, suggests a complex relationship that may influence microbial dynamics and health outcomes in these hosts. Understanding these interactions could provide insights into the epidemiology of infections caused by this strain and its role within the broader microbial community.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_BE036

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_BE036
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_BE036 genome assembly,

Gene Summary

Adenine Count

1162118 bp

Thymine Count

1158927 bp

Guanine Count

1554299 bp

Cytosine Count

1558155 bp

Genome Length

5433499 bp

Protein-coding Genes

4825 genes

Non-Coding Genes

258 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
extracellular solute-binding family protein 3SAMEA3727626_03579Not AvailablePositive3863548 - 386435128549.7
glutamine abc transporter atp-binding proteinSAMEA3727626_03580Not AvailablePositive3864382 - 386590255947.2
ribulose-5-phosphate 4-epimerase related epimerase / aldolaseSAMEA3727626_03581Not AvailablePositive3865903 - 386663127081.4
d-3-phosphoglycerate dehydrogenaseSAMEA3727626_03582Not AvailablePositive3866637 - 386756934167.0
dehydrogenaseSAMEA3727626_03583Not AvailablePositive3867630 - 386842427322.7
putative transport proteinSAMEA3727626_03584Not AvailablePositive3868580 - 386920023046.6
putative abc-type amino acid transport/signal transduction systems periplasmic componentSAMEA3727626_03585Not AvailableNegative3869256 - 387014632196.7
putative transcriptional regulator of fimbrial expressionSAMEA3727626_03586Not AvailablePositive3870374 - 387107526783.0
major type 1 subunit fimbrin (pilin)SAMEA3727626_03587Not AvailablePositive3871179 - 387172719251.8
pilin chaperoneSAMEA3727626_03588Not AvailablePositive3871769 - 387243724811.2

Displaying genes 3681 – 3690 of 5083 in total

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total