Klebsiella pneumoniae strain EuSCAPE_BE041

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_BE041 is a Gram-negative, rod-shaped bacterium that exhibits a facultative anaerobic metabolism, utilizing a chemoheterotrophic energy source. This strain is capable of mobility, possessing flagella, and typically arranges itself in chains, pairs, or as single cells. It thrives optimally at 37°C, categorizing it as mesophilic. The ecological and biological relevance of K. pneumoniae EuSCAPE_BE041 lies in its diverse habitat, primarily associated with various hosts, including Homo sapiens, Gallus gallus, and several other animal and plant species. This strain is noted for its pathogenic potential in humans, being implicated in a range of serious health conditions such as bacteremia, urinary tract infections, pneumonia, and sepsis, among others. Its ability to affect multiple host species suggests a versatile ecological niche and highlights its significance in both human and veterinary medicine. K. pneumoniae EuSCAPE_BE041 does not undergo sporulation and contains a single replicon, enclosed by two membranes. Its free-living biotic relationship underscores its adaptability within various environments. The presence of this strain in different hosts indicates its potential for cross-species transmission and emphasizes the importance of monitoring its pathogenic strains to mitigate health risks associated with infections. The wide range of health effects associated with this bacterium underscores its clinical relevance and necessitates ongoing research into its epidemiology and resistance mechanisms.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_BE041

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_BE041
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_BE041 genome assembly,

Gene Summary

Adenine Count

1202164 bp

Thymine Count

1201952 bp

Guanine Count

1593913 bp

Cytosine Count

1593779 bp

Genome Length

5591808 bp

Protein-coding Genes

5096 genes

Non-Coding Genes

244 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
molybdopterin oxidoreductase fe4s4 regionSAMEA3727631_02220Not AvailableNegative2426814 - 242740121501.9
drug/metabolite transporter permeaseSAMEA3727631_02221Not AvailablePositive2427627 - 242850531348.2
1,2-dihydroxycyclohexa-3,5-diene-1-carboxylate dehydrogenaseSAMEA3727631_02222Not AvailableNegative2428502 - 242927527298.4
benzoate dioxygenase, ferredoxin reductase componentSAMEA3727631_02223Not AvailableNegative2429285 - 243030136715.0
benzoate 1,2-dioxygenase subunit betaSAMEA3727631_02224Not AvailableNegative2430311 - 243079619302.6
2-chlorobenzoate 1,2-dioxygenase, alpha subunitSAMEA3727631_02225Not AvailableNegative2430796 - 243217852545.8
catechol 1,2-dioxygenaseSAMEA3727631_02226Not AvailableNegative2432288 - 243321434290.3
muconolactone isomeraseSAMEA3727631_02227Not AvailableNegative2433281 - 243357111212.5
l-ala-d/l-glu epimeraseSAMEA3727631_02228Not AvailableNegative2433591 - 243470938956.9
pca regulon regulatory protein pcarSAMEA3727631_02229Not AvailablePositive2434963 - 243576028222.5

Displaying genes 2361 – 2370 of 5340 in total

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total