Klebsiella pneumoniae strain EuSCAPE_BE020

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_BE020 is a Gram-negative, rod-shaped bacterium that exhibits a facultative anaerobic metabolism, utilizing a chemoheterotrophic energy source. This strain is capable of mobility, possessing flagella, and typically forms chains, pairs, or single cells. Its optimal growth temperature is 37°C, classifying it as mesophilic. This bacterium is primarily associated with hosts, including Homo sapiens and various other species such as Gallus gallus, Metazoa, and several mammals and birds. Klebsiella pneumoniae strain EuSCAPE_BE020 has been identified as a significant pathogen in humans, causing a wide range of health issues including bacteremia, urinary tract infections, pneumonia, and sepsis. The bacterium can lead to severe conditions such as liver abscesses and meningitis, underscoring its clinical importance. The strain's pathogenicity is particularly concerning in hospital settings, where it can cause infections in individuals with compromised immune systems. Its nonsporulating nature indicates that it does not form spores, which can limit its ability to survive in harsh environments compared to spore-forming bacteria. Ecologically, Klebsiella pneumoniae strain EuSCAPE_BE020 represents a free-living organism that can inhabit diverse environments, potentially affecting various hosts across multiple species. The strain’s ability to thrive in different biological settings may facilitate its transmission and impact on host health, reinforcing the importance of monitoring its prevalence, especially in healthcare contexts.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_BE020

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_BE020
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_BE020 genome assembly,

Gene Summary

Adenine Count

1228622 bp

Thymine Count

1225470 bp

Guanine Count

1603964 bp

Cytosine Count

1654602 bp

Genome Length

5712658 bp

Protein-coding Genes

5112 genes

Non-Coding Genes

276 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
protein co-occurring with transport system proteinSAMEA3727610_04683Not AvailableNegative4988748 - 498936221489.8
xaa-pro dipeptidase pepqSAMEA3727610_04684Not AvailableNegative4989362 - 499069350172.9
multifunctional fatty acid oxidation complex subunit alphaSAMEA3727610_04685Not AvailablePositive4990885 - 499307479265.1
3-ketoacyl-coa thiolaseSAMEA3727610_04686Not AvailablePositive4993084 - 499424741032.8
nad(p)h-flavin reductaseSAMEA3727610_04687Not AvailableNegative4994354 - 499505526384.6
3-polyprenyl-4-hydroxybenzoate carboxy-lyaseSAMEA3727610_04688Not AvailableNegative4995105 - 499658055140.5
transcriptional activator rfahSAMEA3727610_04689Not AvailablePositive4996759 - 499724718286.2
deoxyribonuclease tatdSAMEA3727610_04690Not AvailableNegative4997244 - 499803528756.2
twin-arginine translocation protein tatcSAMEA3727610_04691Not AvailableNegative4998080 - 499885928863.1
twin-arginine translocation protein tatbSAMEA3727610_04692Not AvailableNegative4998862 - 499939819092.5

Displaying genes 4751 – 4760 of 5388 in total

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total