Klebsiella pneumoniae strain EuSCAPE_BE013

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_BE013 is a Gram-negative, rod-shaped bacterium that exhibits a facultative anaerobic metabolism, functioning as a chemoheterotroph. This strain is capable of existing in various cell arrangements, including chains, pairs, and singles, and possesses flagella, enabling mobility. With a mesophilic temperature range, it thrives optimally at 37°C. This bacterium is notably associated with a wide range of hosts, including Homo sapiens, various species of birds, and mammals, indicating its adaptability and potential for zoonotic transmission. Klebsiella pneumoniae strain EuSCAPE_BE013 has been linked to numerous health complications in humans, such as bacteremia, urinary tract infections, pneumonia, and sepsis, among others. The strain's pathogenicity underscores its significance as a human pathogen, capable of causing severe infections. Klebsiella pneumoniae is free-living but is predominantly found in host-associated environments, which may facilitate its transmission and survival across different species. Its ability to cause infections in diverse hosts highlights its ecological versatility and the potential risks it poses to both human health and veterinary contexts. The presence of this strain in various ecological niches suggests a complex interplay between the bacteria and their hosts, which may have implications for the management of infections and understanding the dynamics of antimicrobial resistance.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_BE013

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_BE013
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_BE013 genome assembly,

Gene Summary

Adenine Count

1216937 bp

Thymine Count

1219909 bp

Guanine Count

1603295 bp

Cytosine Count

1617319 bp

Genome Length

5657460 bp

Protein-coding Genes

5018 genes

Non-Coding Genes

300 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
50s ribosomal protein l20SAMEA3727603_03308Not AvailableNegative3567107 - 356746313497.7
50s ribosomal protein l35SAMEA3727603_03309Not AvailableNegative3567514 - 35677117289.38
translation initiation factor if-3SAMEA3727603_03310Not AvailableNegative3567804 - 356823816595.4
threonyl-trna synthetaseSAMEA3727603_03311Not AvailableNegative3568350 - 357027873941.2
uncharacterised proteinSAMEA3727603_03312Not AvailableNegative3570711 - 35709447822.16
membrane proteinSAMEA3727603_03313Not AvailableNegative3571216 - 357197427299.4
6-phosphofructokinase class iiSAMEA3727603_03314Not AvailablePositive3572331 - 357326332591.1
protein of uncharacterised function (duf2622)SAMEA3727603_03315Not AvailablePositive3573358 - 357364210057.7
protein kinase-like proteinSAMEA3727603_03316Not AvailablePositive3573748 - 357462033275.4
transporterSAMEA3727603_03317Not AvailableNegative3574664 - 357540126783.3

Displaying genes 3471 – 3480 of 5318 in total

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total