Klebsiella pneumoniae strain EuSCAPE_BE003

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_BE003 is a Gram-negative, rod-shaped bacterium that exhibits facultative anaerobic metabolism, allowing it to thrive in varying oxygen levels. This strain is identified as a chemoheterotroph, utilizing organic compounds for energy, and it typically grows optimally at 37°C, classifying it as mesophilic. The organism can be found in a host-associated habitat and displays a free-living biotic relationship. In terms of cellular organization, EuSCAPE_BE003 can be observed in chains, pairs, or as singles, and it possesses flagella, indicating its capability for mobility. The strain has a unique genetic structure characterized by a single replicon and is enclosed by two membranes. Klebsiella pneumoniae is known to be pathogenic to humans, causing a range of serious health issues, including bacteremia, urinary tract infections, pneumonia, and various intra-abdominal infections. Other notable infections linked to this strain include meningitis, sepsis, and enteritis, which underline its clinical significance. The strain is associated with a diverse range of hosts, including various mammals, birds, and even plants, reflecting its ecological versatility. This adaptability may facilitate its transmission and persistence in different environments. Overall, Klebsiella pneumoniae strain EuSCAPE_BE003 exemplifies the complexities of microbial life, particularly regarding its pathogenic potential and ecological interactions within host organisms.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_BE003

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_BE003
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_BE003 genome assembly,

Gene Summary

Adenine Count

1122773 bp

Thymine Count

1134774 bp

Guanine Count

1539246 bp

Cytosine Count

1506019 bp

Genome Length

5302812 bp

Protein-coding Genes

4850 genes

Non-Coding Genes

148 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
putative glyoxalase/bleomycin resistance protein/dioxygenaseSAMEA3727595_00347Not AvailablePositive343934 - 34437416018.0
polyphosphate kinaseSAMEA3727595_00348Not AvailablePositive344442 - 34526031401.3
formate dehydrogenase n subunit gammaSAMEA3727595_00349Not AvailableNegative346000 - 34665625678.4
formate dehydrogenase n subunit betaSAMEA3727595_00350Not AvailableNegative346649 - 34753332226.6
formate dehydrogenase-n alpha subunitSAMEA3727595_00351Not AvailableNegative347545 - 34995689952.0
molybdopterin oxidoreductase fe4s4 regionSAMEA3727595_00352Not AvailableNegative350005 - 35059221501.9
drug/metabolite transporter permeaseSAMEA3727595_00353Not AvailablePositive350818 - 35169631378.2
1,2-dihydroxycyclohexa-3,5-diene-1-carboxylate dehydrogenaseSAMEA3727595_00354Not AvailableNegative351693 - 35246627298.4
benzoate dioxygenase, ferredoxin reductase componentSAMEA3727595_00355Not AvailableNegative352476 - 35349236732.0
benzoate 1,2-dioxygenase subunit betaSAMEA3727595_00356Not AvailableNegative353502 - 35398719314.6

Displaying genes 371 – 380 of 4998 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total