Klebsiella pneumoniae strain EuSCAPE_IE009

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_IE009 is a Gram-negative, rod-shaped bacterium that exhibits a facultative anaerobic metabolism, making it a chemoheterotroph. This strain is capable of existing in various cell arrangements including chains, pairs, and singles, and it possesses flagella, indicating mobility. It thrives optimally at 37°C, categorizing it as mesophilic, and has a single replicon and double membrane structure. This strain is primarily host-associated and has been found in a diverse range of hosts, including humans (Homo sapiens), poultry (Gallus gallus), various mammals, and certain aquatic species like zebrafish (Danio rerio). Its ability to inhabit multiple hosts suggests a broad ecological niche and adaptability. Klebsiella pneumoniae EuSCAPE_IE009 is known for its significant pathogenic potential in humans, being associated with numerous health complications such as bacteremia, urinary tract infections, pneumonia, and intra-abdominal infections, among others. The strain is implicated in serious conditions like sepsis and neonatal sepsis, indicating its capacity to cause severe systemic infections. The diverse habitat and wide range of potential hosts underline the ecological versatility of Klebsiella pneumoniae strain EuSCAPE_IE009. Its role as a pathogen in various environments exemplifies the complex interactions between microorganisms and their hosts, highlighting the importance of monitoring and understanding such strains in both clinical and ecological contexts.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_IE009

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_IE009
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_IE009 genome assembly,

Gene Summary

Adenine Count

1201544 bp

Thymine Count

1196502 bp

Guanine Count

1578956 bp

Cytosine Count

1613442 bp

Genome Length

5590444 bp

Protein-coding Genes

5042 genes

Non-Coding Genes

267 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
Lysr family transcriptional regulatorSAMEA3727559_01738Not AvailableNegative1858919 - 185980031639.2
putative integral membrane transport proteinSAMEA3727559_01739Not AvailablePositive1859976 - 186119340869.7
3-oxoacyl-(acyl-carrier-protein) reductaseSAMEA3727559_01740Not AvailableNegative1861190 - 186193925460.6
Lysr family transcriptional regulatorSAMEA3727559_01741Not AvailablePositive1862106 - 186301132993.6
Error-prone lesion bypass dna polymerase vSAMEA3727559_01742Not AvailableNegative1863018 - 186428347301.1
Protein umudSAMEA3727559_01743Not AvailableNegative1864286 - 186470515166.3
Gp22SAMEA3727559_01744Not AvailablePositive1864976 - 18652189386.42
heptosyltransferase family proteinSAMEA3727559_01745Not AvailableNegative1865389 - 186652843176.6
ybak/prolyl-trna synthetase-associated domain proteinSAMEA3727559_01746Not AvailablePositive1866772 - 186727217915.8
inner membrane proteinSAMEA3727559_01747Not AvailablePositive1867389 - 186783515337.7

Displaying genes 1 – 10 of 5309 in total

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
EpnCausesPMC7480896
Emphysematous pyelonephritisCausesPMC7480896
Pulmonary infectionCausesPMC8190614
Primary bacteremiaCausesPMC9427560
Urinary tract infectionsCausesPMC9427560
PneumoniaCausesPMC9427560
Intra-abdominal infectionsCausesPMC9427560
Wound infectionsCausesPMC9427560
PyonephrosisCausesPMC11729731
Psoas abscessCausesPMC11729731

Displaying health effects 31 – 40 of 53 in total