Klebsiella pneumoniae strain EuSCAPE_IE009

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_IE009 is a Gram-negative, rod-shaped bacterium that exhibits a facultative anaerobic metabolism, making it a chemoheterotroph. This strain is capable of existing in various cell arrangements including chains, pairs, and singles, and it possesses flagella, indicating mobility. It thrives optimally at 37°C, categorizing it as mesophilic, and has a single replicon and double membrane structure. This strain is primarily host-associated and has been found in a diverse range of hosts, including humans (Homo sapiens), poultry (Gallus gallus), various mammals, and certain aquatic species like zebrafish (Danio rerio). Its ability to inhabit multiple hosts suggests a broad ecological niche and adaptability. Klebsiella pneumoniae EuSCAPE_IE009 is known for its significant pathogenic potential in humans, being associated with numerous health complications such as bacteremia, urinary tract infections, pneumonia, and intra-abdominal infections, among others. The strain is implicated in serious conditions like sepsis and neonatal sepsis, indicating its capacity to cause severe systemic infections. The diverse habitat and wide range of potential hosts underline the ecological versatility of Klebsiella pneumoniae strain EuSCAPE_IE009. Its role as a pathogen in various environments exemplifies the complex interactions between microorganisms and their hosts, highlighting the importance of monitoring and understanding such strains in both clinical and ecological contexts.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_IE009

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_IE009
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_IE009 genome assembly,

Gene Summary

Adenine Count

1201544 bp

Thymine Count

1196502 bp

Guanine Count

1578956 bp

Cytosine Count

1613442 bp

Genome Length

5590444 bp

Protein-coding Genes

5042 genes

Non-Coding Genes

267 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
ribosomal large subunit pseudouridine synthase aSAMEA3727559_02653Not AvailablePositive2878335 - 287899425015.3
phosphoribosyl-dephospho-coa transferaseSAMEA3727559_02654Not AvailableNegative2879069 - 287960820091.2
malate na(+) symporterSAMEA3727559_02655Not AvailableNegative2879788 - 288115248154.8
two-component sensor kinase for citrateSAMEA3727559_02656Not AvailablePositive2881477 - 288310260789.8
two-component response regulator for citrateSAMEA3727559_02657Not AvailablePositive2883092 - 288379026200.5
dnaj-like protein djlaSAMEA3727559_02658Not AvailableNegative2883823 - 288465030961.5
outer membrane protein impSAMEA3727559_02659Not AvailablePositive2884894 - 288724288493.1
survival protein sura precursor (peptidyl-prolyl cis-trans isomerase sura)SAMEA3727559_02660Not AvailablePositive2887297 - 288858347065.3
4-hydroxythreonine-4-phosphate dehydrogenaseSAMEA3727559_02661Not AvailablePositive2888589 - 288957835145.9
dimethyladenosine transferaseSAMEA3727559_02662Not AvailablePositive2889575 - 289039630584.2

Displaying genes 2821 – 2830 of 5309 in total

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total