Klebsiella pneumoniae strain EuSCAPE_HR088

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_HR088 is a Gram-negative, rod-shaped bacterium that exhibits mobility due to the presence of flagella. It is a facultative anaerobe, allowing it to thrive in both aerobic and anaerobic environments, with an optimal growth temperature of 37°C, categorizing it as mesophilic. This strain is chemoheterotrophic, indicating that it derives its energy from organic compounds. The bacterium primarily resides in association with various hosts, including Homo sapiens, Gallus gallus, and multiple other metazoan and plant species. Its biotic relationship is classified as free-living, emphasizing its adaptability to different environments. Klebsiella pneumoniae strain EuSCAPE_HR088 has been linked to a range of significant health effects in humans, including bacteremia, urinary tract infections, pneumonia, and several intra-abdominal infections. The strain is noted for its pathogenicity, particularly in causing sepsis and neonatal infections, which highlights its potential impact on human health. The strain possesses a single replicon and is characterized by a double membrane structure, typical of Gram-negative bacteria. Understanding the ecological role and pathogenic potential of Klebsiella pneumoniae strain EuSCAPE_HR088 is crucial for developing effective treatment and prevention strategies, particularly given its association with severe infections in vulnerable populations. The diverse host range underlines its ecological versatility, which may contribute to its persistence and spread in various environments.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_HR088

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_HR088
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_HR088 genome assembly,

Gene Summary

Adenine Count

1162716 bp

Thymine Count

1168567 bp

Guanine Count

1583414 bp

Cytosine Count

1549490 bp

Genome Length

5464187 bp

Protein-coding Genes

0 genes

Non-Coding Genes

0 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
protein of uncharacterised function (duf2810)SAMEA3721120_02786Not AvailablePositive3006688 - 300705013772.9
l-lactate permeaseSAMEA3721120_02787Not AvailablePositive3007336 - 300899159313.9
dna-binding transcriptional repressor lldrSAMEA3721120_02788Not AvailablePositive3008988 - 300976128943.5
l-lactate dehydrogenaseSAMEA3721120_02789Not AvailablePositive3009761 - 301094543010.7
trna (cytosine34-2'-o-)-methyltransferaseSAMEA3721120_02790Not AvailablePositive3011038 - 301151117462.0
serine acetyltransferaseSAMEA3721120_02791Not AvailableNegative3011614 - 301243529307.4
glycerol-3-phosphate dehydrogenaseSAMEA3721120_02792Not AvailableNegative3012509 - 301352836235.0
protein export cytoplasm chaperone protein secbSAMEA3721120_02793Not AvailableNegative3013528 - 301399517191.2
glutaredoxin 3 (grx3)SAMEA3721120_02794Not AvailableNegative3014056 - 30143079149.05
rhodanese-related sulfurtransferaseSAMEA3721120_02795Not AvailableNegative3014412 - 301484315587.2

Displaying genes 2871 – 2880 of 5182 in total

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total