Klebsiella pneumoniae strain EuSCAPE_BE022

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_BE022 is a Gram-negative, rod-shaped bacterium that exhibits a variety of pathogenic properties, particularly in humans. It is classified as a facultative anaerobe, allowing it to thrive in both aerobic and anaerobic environments, and is a chemoheterotroph, deriving its energy from organic compounds. This strain is capable of existing in diverse habitats, primarily associated with hosts, including Homo sapiens, various animal species, and even some plants. The organism typically forms chains, pairs, and singles and possesses flagella, which contribute to its mobility. EuSCAPE_BE022 has a mesophilic temperature range, with an optimal growth temperature of 37°C, aligning with the human body temperature, which is conducive for pathogenicity. Klebsiella pneumoniae strain EuSCAPE_BE022 is implicated in a range of serious health conditions, including but not limited to bacteremia, urinary tract infections, pneumonia, and various intra-abdominal infections. Its ability to cause diseases such as neonatal sepsis and pyogenic liver abscess underscores its significant role as a human pathogen. Given its free-living nature and broad host range, this strain can adapt to different environments while posing health risks to both humans and animals. This adaptability and pathogenic potential highlight the ecological significance of Klebsiella pneumoniae in both clinical and environmental contexts, emphasizing the need for ongoing surveillance and research into its behavior and resistance mechanisms.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_BE022

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_BE022
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_BE022 genome assembly,

Gene Summary

Adenine Count

1232818 bp

Thymine Count

1230049 bp

Guanine Count

1606709 bp

Cytosine Count

1661960 bp

Genome Length

5731536 bp

Protein-coding Genes

5027 genes

Non-Coding Genes

435 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
phosphogluconate repressor hexr, rpir familySAMEA3727612_00945Not AvailablePositive988069 - 98895632616.2
pyruvate kinaseSAMEA3727612_00946Not AvailablePositive989082 - 99052451425.2
lipid a biosynthesis (kdo) 2-(lauroyl)-lipid iva acyltransferaseSAMEA3727612_00947Not AvailableNegative990565 - 99153937455.8
cell wall endopeptidaseSAMEA3727612_00948Not AvailableNegative991657 - 99297648948.3
high-affinity zinc transporter periplasmic componentSAMEA3727612_00949Not AvailableNegative992992 - 99393634078.6
zinc abc transporterSAMEA3727612_00950Not AvailablePositive994015 - 99476727603.1
zinc abc transporterSAMEA3727612_00951Not AvailablePositive994767 - 99555227576.3
holliday junction dna helicase ruvbSAMEA3727612_00952Not AvailableNegative995616 - 99662637147.9
holliday junction dna helicase ruvaSAMEA3727612_00953Not AvailableNegative996635 - 99724622130.0
holliday junction resolvaseSAMEA3727612_00954Not AvailableNegative997326 - 99784718627.7

Displaying genes 1361 – 1370 of 5462 in total

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total